Dependence of the Bi-functional Nature of a Sialyltransferase from Neisseria meningitidis on a Single Amino Acid Substitution

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 12785-12790

  Wakarchuk, Warren W ^a   Watson, David ^b   St Michael, Frank ^b   Li, Jianjun ^b   Wu, Yuyang ^b   Brisson, Jean Robert ^b   Young, N Martin ^b   Gilbert, Michel ^b  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CARBOHYDRATES; CATALYST ACTIVITY; ENZYME KINETICS; GENES; MUTAGENESIS;

LIPOOLIGOSACCHARIDES;

ENZYMES;

ALPHA 2,3 SIALYLTRANSFERASE; AMINO ACID; EPITOPE; LIPOPOLYSACCHARIDE; N ACETYLNEURAMINIC ACID; SIALYLTRANSFERASE; UNCLASSIFIED DRUG; BETA D GALACTOSIDE ALPHA 2 6 SIALYLTRANSFERASE; BETA GALACTOSIDE ALPHA 2,3 SIALYLTRANSFERASE; BETA-D-GALACTOSIDE ALPHA 2-6-SIALYLTRANSFERASE; BETA-GALACTOSIDE ALPHA-2,3-SIALYLTRANSFERASE; GLYCOSIDE; GLYCOSYLTRANSFERASE; LIPID LINKED OLIGOSACCHARIDES; LIPID-LINKED OLIGOSACCHARIDES; RECOMBINANT PROTEIN;

ALLELE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL STRAIN; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME MECHANISM; GENE DISRUPTION; GENE TRANSFER; IN VITRO STUDY; NEISSERIA MENINGITIDIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REACTION ANALYSIS; SITE DIRECTED MUTAGENESIS; BIOSYNTHESIS; CARBOHYDRATE ANALYSIS; CHEMISTRY; CLASSIFICATION; ENZYME SPECIFICITY; ENZYMOLOGY; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; NEISSERIA; NEISSERIA MENINGITIDIS;

AMINO ACID SUBSTITUTION; CARBOHYDRATE SEQUENCE; GLYCOSIDES; GLYCOSYLTRANSFERASES; LIPOPOLYSACCHARIDES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEISSERIA MENINGITIDIS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; RECOMBINANT PROTEINS; SIALYLTRANSFERASES; SUBSTRATE SPECIFICITY;

EID: 0035918185     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011293200     Document Type: Article

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