Positively charged residues at the N-terminal arm of the homeodomain are required for efficient DNA binding by homeodomain-leucine zipper proteins

Journal of Molecular Biology

Volumn 308, Issue 1, 2001, Pages 39-47

  Palena, Claudia M ^a   Tron, Adriana E ^a   Bertoncini, Carlos W ^a   Gonzalez, Daniel H ^a   Chan, Raquel L ^a  

^a UNIVERSIDAD NACIONAL DEL LITORAL   (Argentina)

Author keywords

DNA binding; Hd Zip protein; Homeodomain; Leucine zipper; N terminal arm

Indexed keywords

HOMEODOMAIN PROTEIN; LEUCINE ZIPPER PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; DISSOCIATION CONSTANT; DNA BINDING; EVOLUTION; PLANT; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STRUCTURE; SEQUENCE ANALYSIS;

ANIMALIA; FUNGI; METAZOA;

EID: 0035917325     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4563     Document Type: Article

References (32)

1. Homeo boxes in the study of development
2. Homeobox proteins as sequence-specific transcription factors
3. Homeodomain proteins
4. The structure of the Antennapedia homeodomain determined by MNR spectroscopy in solution: Comparison with prokaryotic repressors
5. Nuclear magnetic resonance solution structure of the fushi tarazu homeodomain from Drosophila and comparison with the Antennapedia homeodomain
6. The three dimensional solution structure of the NK-2 homeodomain from Drosophila
7. Crystal structure of an engrailed homeodomain-DNA complex at 2.8 Å resolution: A framework for understanding homeodomain-DNA interactions
8. Protein-DNA contacts in the structure of a homeodomain-DNA complex determined by nuclear magnetic resonance spectroscopy in solution
9. Crystal structure of a MATα2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions
10. Homeodomain-DNA recognition
11. Secondary structure determination for the Antennapedia homeodomain by nuclear magnetic resonance and evidence for a helix-turn-helix motif
12. DNA binding properties of the purified Antennapedia homeodomain
13. DNA-binding specificity of the fushi tarazu homeodomain
14. The interaction with DNA of wild-type and mutant fushi tarazu homeodomains
15. Design of a "minimAl" homeodomain: The N-terminal arm modulates DNA binding affinity and stabilizes homeodomain structure
16. Homeoboxes in plant development
17. A novel class of proteins containing a homeodomain with a closely linked leucine zipper motif
18. HD-Zip proteins: Members of an Arabidopsis homeodomain protein superfamily
19. The Athb-1 and -2 HD-Zip domains homodimerize forming complexes of different DNA binding specificities
20. A monomer-dimer equilibrium modulates the interaction of the sunflower homeodomain leucine-zipper protein Hahb-4 with DNA
21. DNA binding specificity of homeodomains
22. Interaction between proteins containing homeodomains associated to leucine zippers from sunflower
23. DNA-binding specificity on the homeodomain-leucine zipper domain
24. Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules
25. High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA
26. The degree of variation in DNA sequence recognition among four Drosophila homeotic proteins
27. A molecular code dictates sequence-specific DNA recognition by homeodomains
28. Did homeodomain proteins duplicate before the origin of angiosperms, fungi and metazoa?
29. Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX; Iroquois, TGIF) reveals a novel domain conserved between plants and animals
30. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
31. Expression of sunflower homeodomain containing proteins in Escherichia coli: Purification and functional studies
32. A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G-250