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Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 12, 2001, Pages 1527-1531

Conversion of cyclic nonaketides to lovastatin and compactin by a lovC deficient mutant of Aspergillus terreus

(4) Auclair, Karine a Kennedy, Jonathan b,c Hutchinson, C Richard b,c Vederas, John C a

a UNIVERSITY OF ALBERTA (Canada)

b UNIVERSITY OF WISCONSIN MADISON (United States)

c KOSAN BIOSCIENCES INC (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4A,5 DIHYDROMONACOLIN L; BACTERIAL ENZYME; BACTERIAL PROTEIN; COMPACTIN; HYPOCHOLESTEROLEMIC AGENT; LOVASTATIN DIKETIDE SYNTHASE; MEVINOLIN; MONACOLIN J; MONACOLIN L; MUTANT PROTEIN; POLYKETIDE; SYNTHETASE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS TERREUS; BACTERIUM; BIOSYNTHESIS; CHEMICAL MODIFICATION; CHEMICAL REACTION; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; FUNGUS; GENE; MUTATION; NONHUMAN; PRECURSOR; PROTEIN ANALYSIS; REACTION ANALYSIS; STOICHIOMETRY;

ANTICHOLESTEREMIC AGENTS; ASPERGILLUS; FUNGAL PROTEINS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LOVASTATIN; MULTIENZYME COMPLEXES;

EID: 0035907461 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(01)00290-6 Document Type: Article

Times cited : (32)

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