Identification of E2F-1/Cyclin A antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 18, 2001, Pages 2449-2452

  Sharma, Sushil K ^a   Ramsey, Timothy M ^a   Chen, Ying Nan P ^a   Chen, Weichun ^a   Martin, Mary S ^a   Clune, Kenneth ^a   Sabio, Michael ^a   Bair, Kenneth W ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLLYSYLARGINYLLYSYLLEUCYLPHENYLALANYLGLYCINE; ANTINEOPLASTIC AGENT; CYCLIN A; CYCLIN DEPENDENT KINASE INHIBITOR; LACTAM DERIVATIVE; OCTAPEPTIDE; PROLYLALANYLLYSYLARGINYLLYSYLPHENYLALANYLGLYCINE; PROLYLLEUCYLSPIROLACTAM; PROLYLVALYLLYSYLARGINYLARGINYLLEUCYLASPARTYLLEUCINE; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL REACTION; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REACTION ANALYSIS;

AMINO ACID SEQUENCE; BINDING SITES; BIOCHEMISTRY; CELL CYCLE PROTEINS; COMBINATORIAL CHEMISTRY TECHNIQUES; CONSERVED SEQUENCE; CYCLIN A; DNA-BINDING PROTEINS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; ENZYME-LINKED IMMUNOSORBENT ASSAY; INHIBITORY CONCENTRATION 50; PEPTIDE LIBRARY; PEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS;

EID: 0035903893     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00486-3     Document Type: Article

References (14)