Inactivation of DsbA alters the behaviour of Shigella flexneri towards murine and human-derived macrophage-like cells

FEMS Microbiology Letters

Volumn 204, Issue 1, 2001, Pages 81-88

  Yu, Jun ^a   Oragui, Emmanuelle E ^a   Stephens, Alick ^a   Kroll, J Simon ^a   Venkatesan, Malabi M ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

DsbA; Macrophage; Shigella flexneri

Indexed keywords

CHLOROQUINE; GENTAMICIN; INTERLEUKIN 1BETA; OXIDOREDUCTASE; THIOL DISULFIDE OXIDOREDUCTASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BACTERIAL GROWTH; BACTERIUM MUTANT; CELL KILLING; CELL VACUOLE; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOSOL; ENZYME INACTIVATION; HOST CELL; HUMAN; HUMAN CELL; IMMUNOGENICITY; MACROPHAGE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHIGELLA FLEXNERI; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; APOPTOSIS; CELL LINE; GENE DELETION; HUMANS; INTERLEUKIN-1; MACROPHAGES; MICE; MICROSCOPY, ELECTRON; PHAGOCYTOSIS; PROTEIN DISULFIDE-ISOMERASE; SHIGELLA FLEXNERI; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS; VACUOLES; VIRULENCE;

EID: 0035899893     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(01)00381-0     Document Type: Article

References (24)

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2. The Escherichia coli dsbA gene is partly transcribed from the promoter of a weakly expressed upstream gene
3. A bacterial invasin induces apoptosis by directly binding ICE
4. Human monocyte-derived macrophages infected with virulent Shigella flexneri in vitro undergo a rapid cytolytic event similar to oncosis but not apoptosis
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7. Human myeloid cell lines
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