Crystal structure of the catalytic core component of the alkylhydroperoxide reductase AhpF from Escherichia coli

Journal of Molecular Biology

Volumn 307, Issue 1, 2001, Pages 1-8

  Bieger, Boris ^a   Essen, Lars Oliver ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

Alkylhydroperoxide reductase; Crystal structure; Disulphide oxidoreductase; FAD; Reactive oxygen

Indexed keywords

FLAVINE ADENINE NUCLEOTIDE; HYDROPEROXIDE; HYDROPEROXIDE REDUCTASE; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

AEROBIC BACTERIUM; AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; DIMERIZATION; ELECTRON TRANSPORT; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; SEQUENCE ANALYSIS;

ESCHERICHIA COLI;

EID: 0035896010     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4441     Document Type: Article

References (28)

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3. Requirement for the two Ahpf cystine disulfide centers in catalysis of peroxide reduction by alkyl hydroperoxide reductase
4. Roles for the two cysteine residues of AhpC in catalysis of peroxide reduction by alkyl hydroperoxide reductase from Salmonella Typhimurium
5. Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazid
6. Crystal structure of Arabidopsis thaliana NADPH dependent thioredoxin reductase at 2.5 Å resolution
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9. A protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus contains two thioredoxin fold units
10. AhpF can be dissected into two functional units: Tandem repeats of two thioredoxin-like folds in the N terminus mediate electron transfer from the thioredoxin reductase-like C terminus to AhpC
11. The structure of the flavoenzyme glutathione reductase
12. A single dipeptide sequence modulates the redox properties of a whole enzyme family
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15. Twists in catalysis: Alternating conformations of Escherichia coli thioredoxin reductase
16. Thioredoxin reductase thioredoxin fusion enzyme from Mycobacterium leprae: Comparison with the separately expressed thioredoxin reductase
17. Crystallization and preliminary X-ray analysis of the catalytic core of the alkylhydroperoxide reductase component AhpF from Escherichia coli
18. Processing of X-ray diffraction data collected in oscillation mode
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