TRP proteins: Novel therapeutic targets for regional blood pressure control?

Circulation Research

Volumn 88, Issue 3, 2001, Pages 256-259

  Schilling, William P ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b METROHEALTH MEDICAL CENTER   (United States)

Author keywords

Adrenergic receptors; Ca2+ channels; Smooth muscle; Store operated

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; ALPHA ADRENERGIC RECEPTOR; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CATECHOLAMINE; DIACYLGLYCEROL; LANTHANIDE; NIFEDIPINE; PHOSPHOLIPASE C; PROTEIN; PROTEIN KINASE C; TRP PROTEIN; UNCLASSIFIED DRUG;

AUTONOMIC NERVOUS SYSTEM; BLOOD PRESSURE REGULATION; BLOOD VESSEL TONE; CALCIUM TRANSPORT; CATECHOLAMINE RELEASE; EDITORIAL; ENZYME ACTIVATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR INTRINSIC ACTIVITY; SEQUENCE HOMOLOGY; SMOOTH MUSCLE FIBER; VASCULAR RESISTANCE;

EID: 0035895591     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.88.3.256     Document Type: Editorial

References (41)

1. Excitation-contraction coupling in gastrointestinal and other smooth muscle cells
2. Ion channels in vascular smooth muscle: Alterations in essential hypertension
3. Store depletion and calcium influx
4. CRAC) in Jurkat T cells
5. 2+ store depletion in vascular smooth muscle cells
6. 2+ signaling in arterial myocytes
7. 2+ mobilization
8. Receptor-mediated activation of recombinant Trpl expressed in Sf9 insect cells
9. 2+ influx pathway in Sf9 insect cells following expression of the transient receptor potential-like (trpl) protein of Drosophila
10. Activation of recombinant Trp by thapsigargin in Sf9 insect cells
11. The Drosophila cation channel trpl expressed in insect Sf9 cells is stimulated by agonists of G-protein-coupled receptors
12. 11 subunits
13. Coassembly of TRP and TRPL produces a distinct store-operated conductance
14. TRPC1, a human homolog of a Drosophila store-operated channel
15. Molecular cloning of a widely expressed human homologue for the Drosophila trp gene
16. A mammalian capacitative calcium entry channel homologous to Drosophila TRP and TRPL
17. q class of G protein
18. 2+ entry
19. 2+ channel from mouse brain
20. Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7
21. TRP2: A candidate transduction channel for mammalian pheromone sensory signaling
22. 2+ entry
23. Expression of TRPC3 in Chinese hamster ovary cells results in calcium-activated cation currents not related to store depletion
24. 2+ influx in stably transfected HEK293 cells
25. Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol
26. Receptor-mediated regulation of the non-selective cation channels TRPC4 and TRPC5
27. Properties of heterologously expressed hTRP3 channels in bovine pulmonary artery endothelial cells
28. Functional expression of TrpCl: A human homologue of the Drosophila Trp channel
29. A novel capacitative calcium entry channel expressed in excitable cells
30. 2+
31. Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL
32. Regulation of Drosophila transient receptor potential-like (TrpL) channels by phospholipase C-dependent mechanisms
33. Functional interaction between InsP3 receptors and store-operated Htrp3 channels
34. 2+ entry in HEK-293 cells
35. 2+ influx mechanism in salivary gland cells
36. Activation of a TRPC3-dependent cation channel current through the neurotrophin BDNF
37. 2+-like channels in adrenal cells
38. 2+-permeable cation channel
39. Properties of single Drosophila trp1 channels expressed in Sf9 insect cells
40. Differential expression of mammalian Trp homologues across tissues and cell lines
41. 2+ channels in native vascular smooth muscle cells