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Volumn 177, Issue 3, 2001, Pages 256-263

Rottlerin stimulates metallothionein gene expression but inhibits metal transport in Chinese hamster ovary cells

Author keywords

CHO cells; Gene expression; Metal transport; Metallothionein; MTF 1; Protein synthesis; Rottlerin

Indexed keywords

GENE PRODUCT; ISOPROTEIN; METALLOTHIONEIN; PROTEIN KINASE INHIBITOR; ROTTLERIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MTF1; UNCLASSIFIED DRUG; ZINC;

EID: 0035894342     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.2001.9299     Document Type: Article
Times cited : (5)

References (32)
  • 8
    • 0028593507 scopus 로고
    • Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter element
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5016-5023
    • Dalton, T.P.1    Palmiter, R.D.2    Andrews, G.K.3
  • 10
    • 0021821539 scopus 로고
    • Alpha-interferon-induced transcription of HLA and metallothionein genes containing homologous upstream sequences
    • (1985) Nature , vol.314 , pp. 637-639
    • Friedman, R.L.1    Stark, G.R.2
  • 14
    • 0021807207 scopus 로고
    • Metallothionein: Proteins in search of function
    • (1985) Cell , vol.41 , pp. 9-10
    • Karin, M.1
  • 17
    • 0033538006 scopus 로고    scopus 로고
    • Protein kinase inhibitor H7 blocks the induction of immediate-early genes zif268 and c-fos by a mechanism unrelated to inhibition of protein kinase C but possibly related to inhibition of phosphorylation of RNA polymerase II
    • (1999) J. Biol. Chem. , vol.274 , pp. 10430-10438
    • Kumahara, E.1    Ebihara, T.2    Saffen, D.3
  • 20
    • 0019865716 scopus 로고
    • The induced synthesis of metallothionein in various tissues of rat response to metals. I. Effect of repeated injection of cadmium salts
    • (1981) Toxicology , vol.22 , pp. 91-101
    • Onosaka, S.1    Cherian, M.G.2
  • 22
    • 0028125990 scopus 로고
    • Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1219-1223
    • Palmiter, R.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.