Detection of occult metastatic breast cancer cells in blood by a multimolecular marker assay: Correlation with clinical stage of disease

Cancer Research

Volumn 61, Issue 24, 2001, Pages 8845-8850

  Taback, B ^a   Chan, A D ^a   Kuo, C T ^a   Bostick, P J ^a   Wang, H J ^a   Giuliano, A E ^a   Hoon, D S B ^a  

^a JOHN WAYNE CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 1,4 N ACETYLGALACTOSAMINYLTRANSFERASE; CHORIONIC GONADOTROPIN BETA SUBUNIT; MELANOMA ANTIGEN 3; MESSENGER RNA; N ACETYLGALACTOSAMINYLTRANSFERASE; SCATTER FACTOR RECEPTOR; TUMOR ANTIGEN; TUMOR MARKER; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ASSAY; AUTOANALYSIS; BLOOD SAMPLING; BREAST CANCER; CANCER CELL; CANCER GROWTH; CANCER SIZE; CANCER STAGING; CHEMOLUMINESCENCE; CONTROLLED STUDY; DIAGNOSTIC VALUE; HUMAN; HUMAN CELL; HUMAN TISSUE; METASTASIS; MOLECULE; PARAMETER; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, NEOPLASM; BREAST NEOPLASMS; CHORIOCARCINOMA; CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN; FEMALE; HUMANS; N-ACETYLGALACTOSAMINYLTRANSFERASES; NEOPLASM CIRCULATING CELLS; NEOPLASM PROTEINS; NEOPLASM STAGING; PROTO-ONCOGENE PROTEINS C-MET; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 0035893550     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Ten-year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with or without radiation
2. The interrelationship of hematogenous and lymphatic tumor cell dissemination
3. Sensitive detection of occult breast cancer by the reverse-transhiptase polymerase chain reaction
4. Utilization of polymerase chain reaction technology in the detection of solid tumors
5. Detection of metastatic breast cancer by β-hCG polymerase chain reaction
6. Putative markers for the detection of breast carcinoma cells in blood
7. Quantitative polymerase chain reaction for the detection of micrometastases in patients with breast cancer
8. Molecular detection of circulating solid carcinoma cells in the peripheral blood: The concept of early systemic disease
9. The detection of breast carcinoma micrometastases in axillary lymph nodes by reverse transcriptase- polymerase chain reaction
10. Evaluation of breast tumour cell contamination in the bone marrow and leukapheresis collections by RT-PCR for cytokeratin-19 mRNA
11. Detection of intraoperative tumor cell dissemination in patients with breast cancer by use of reverse transcription and polymerase chain reaction
12. Detection of epithelial cancer cells in peripheral blood by reverse transcriptasepolymerase chain reaction
13. Comparison of molecular cytokeratin 19 reverse transcriptase polymerase chain reaction (CK 19 RT-PCR) and immunocytochemical detection of micrometastatic breast cancer cells in hematopoietic harvests
14. Detection of micrometastasis by cytokeratin RT-PCR is limited due to stable background transcription in granulocytes
15. Minimal illegitimate levels of cytokeratin K19 expression in mononucleated blood cells detected by a reverse transcription PCR method (RT-PCR)
16. Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients
17. Melanoma-associated antigens as messenger RNA detection markers for melanoma
18. 2000 Update of recommendations for the use of tumor markers in breast and colorectal cancer: Clinical practice guidelines of the American Society of Clinical Oncology
19. Breast cancer heterogeneity: Evaluation of clonality in primary and metastatic lesions
20. Tumor-antigen heterogeneity of disseminated breast cancer cells: Implications for immunotherapy of minimal residual disease
21. Detection of tyrosinase mRNA in melanoma by reverse transcription-PCR and electrochemiluminescence
22. The β subunit of human chorionic gonadotropin is encoded by multiple genes
23. Human chorionic gonadotropin-β subunit gene expression in cultured human fetal and cancer cells of different types and origins
24. Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors
25. The cell dissociation and motility triggered by scatter factor/hepatocyte growth factor are mediated through the cytoplasmic domain of the c-Met receptor
26. Interleukin 4 inhibits hepatocyte growth factor-induced invasion and migration of colon carcinomas
27. Expression of c-met is a strong independent prognostic factor in breast carcinoma
28. Modulation of human melanoma cells by interleukin-4 and in combination with γ-interferon or α-tumor necrosis factor
29. Assessment of messenger RNA of β 1->4-N- acetylgalactosaminyl-transferase as a molecular marker for metastatic melanoma
30. Ganglioside GM2 as a human tumor antigen (OFA-1-1)
31. Role of gangliosides in tumor progression
32. Development of a human monoclonal antibody to ganglioside GM2 with potential for cancer treatment
33. Effect of a chimeric anti-ganglioside GM2 antibody on ganglioside GM2-expressing human solid tumors in vivo
34. Identification and intracellular location of MAGE-3 gene product
35. Expression of MAGE and BAGE genes in Japanese breast cancers
36. Expression of the MAGE gene family in primary and metastatic human breast cancer: Implications for tumor antigen-specific immunotherapy
37. Detection of metastases in sentinel lymph nodes of breast cancer patients by multiple-marker RT-PCR
38. Molecular detection of metastatic pancreatic carcinoma cells using a multimarker reverse transcriptase-polymerase chain reaction assay
39. Molecular strategy for detecting metastatic cancers with use of multiple tumor-specific MAGE-A genes
40. Adjuvant therapy for node-negative breast cancer. The use of prognostic factors in selecting patients
41. The role of chemotherapy for node-negative breast cancer
42. Natural history of small breast cancers
43. Prognostic significance of occult metastases detected by sentinel lymphadenectomy and reverse transcriptase-polymerase chain reaction in early-stage melanoma patients
44. Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer
45. Detection of tumor cells in bone marrow of patients with primary breast cancer: A prognostic factor for distant metastasis