Influence of electrochemical properties in determining the sensitivity of [4Fe-4S] clusters in proteins to oxidative damage

Biochemical Journal

Volumn 360, Issue 3, 2001, Pages 717-726

  Tilley, G J ^a   Camba, R ^a   Burgess, B K ^a   Armstrong, F A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Electron transfer; Ferredoxin; Iron sulphur cluster; Oxidation; Voltammetry

Indexed keywords

ELECTROCHEMISTRY; ENZYMES; OXIDATION; PROTEINS;

ELECTROCHEMICAL PROPERTIES;

BIOCHEMISTRY;

FERREDOXIN; IRON SULFUR PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CLOSTRIDIUM PASTEURIANUM; DESULFOVIBRIO; ELECTROCHEMISTRY; ELECTRON TRANSPORT; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PYROCOCCUS FURIOSUS; THAUERA AROMATICA;

AMINO ACID SEQUENCE; ELECTROCHEMISTRY; FERREDOXINS; IRON-SULFUR PROTEINS; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; OXIDATION-REDUCTION; POTENTIOMETRY; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; SEQUENCE ALIGNMENT;

AZOTOBACTER; AZOTOBACTER VINELANDII; CLOSTRIDIUM; CLOSTRIDIUM PASTEURIANUM; DESULFOVIBRIO; DESULFOVIBRIO AFRICANUS; PYROCOCCUS; PYROCOCCUS FURIOSUS; THAUERA; THAUERA AROMATICA;

EID: 0035893417     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3600717     Document Type: Article

References (40)

1. Iron-sulfur clusters: Nature's modular, multipurpose structures
2. Aconitase as iron-sulfur protein, enzyme and iron-regulatory protein
3. Iron-sulfur proteins: Ancient structures, still full of surprises
4. Voltammetric studies of the reactions of iron-sulphur clusters ([3Fe-4S] or [M3Fe-4S]) formed in Pyrococcus furiosus ferredoxin
5. Electrochemical potential and pH dependences of [3Fe-4S] ↔ [M3Fe-4S] cluster transformations (M = Fe, Zn, Co and Cd) in ferredoxin III from Desulfovibrio africanus and detection of a cluster with M = Pb
6. Electrochemical and spectroscopic characterization of the conversion of the 7Fe into the 8Fe form of Ferredoxin-III from Desulfovibrio africanus - Identification of a [4Fe-4S] cluster with one non-cysteine ligand
7. New insights, ideas and unanswered questions concerning iron-sulfur clusters in mitochondria
8. In vivo detection of a 3 iron cluster in fumarate reductase from Escherichia coli
9. Evidence for [2Fe-2S], [3Fe-XS], and [4Fe-4S] clusters in succinate dehydrogenase
10. Magnetic circular dichroism studies of succinate dehydrogenase - Evidence for [2Fe-2S], [3Fe-XS], and [4Fe-4S] centers in reconstitutively active enzyme
11. The high-potential iron-sulfur center in Escherichia coli fumarate reductase is a three-iron cluster
12. Desulfovibrio gigas hydrogenase - Redox properties of the nickel and iron-sulfur centers
13. Investigations of the oxidative disassembly of Fe-S clusters in Clostridium pasteurianum ferredoxin using pulsed protein film voltammetry
14. 4] cluster. Site-directed mutagenesis and NMR studies as a probe of cluster chemistry
15. 4] cluster in Chromatium vinosum high potential iron protein: The role of core aromatic residues in defining cluster redox chemistry
16. 4] cluster
17. Structure-function correlations in high-potential iron proteins
18. Applications of voltammetric methods for probing the chemistry of redox proteins
19. Reactions of complex metalloproteins studied by protein-film voltammetry
20. Investigation of metal-ion uptake reactivities of [3Fe-4S] clusters in proteins - Voltammetry of co-adsorbed terredoxin aminocyclitol films at graphite electrodes and spectroscopic identification of transformed clusters
21. Novel redox chemistry of [3Fe-4S] clusters: Electrochemical characterization of the all-Fe(II) form of the [3Fe-4S] cluster generated reversibly in various proteins and its spectroscopic investigation in Sulfolobus acidocaldarius ferredoxin
22. Very rapid, cooperative two-electron/two-proton redox reactions of [3Fe-4S] clusters: Detection and analysis by protein-film voltammetry
23. 2+/+ protein
24. ΔT14/ΔD15 Azotobacten vinelandii ferredoxin I: Creation of a new CysXXCysXXCys motif that ligates a [4Fe-4S] cluster
25. 2+ conversion in vitro but not in vivo
26. 2+/+ cluster
27. Electrochemical and spectroscopic characterization of the 7Fe Form of ferredoxin III from Desulfovibrio africanus
28. A novel and remarkably thermostable ferredoxin from the hyperthermophilic archaebacterium Pyrococcus funosus
29. Low-temperature magnetic circular dichroism evidence for the conversion of 4-iron-sulfur clusters in a ferredoxin from Clostridium pasteurianum into 3-iron-sulfur clusters
30. Unusual spectroscopic and electrochemical properties of the 2[4Fe-4S] ferredoxin of Thauera aromatica
31. Azotobacter vinelandii ferredoxin-I - Aspartate-15 facilitates proton transfer to the reduced [3Fe-4S] cluster
32. Voltammetric studies of redox-active centers in metalloproteins adsorbed on electrodes
33. Direct detection and measurement of electron relays in a multicentered enzyme: Voltammetry of electrode-surface films of E. coli fumarate reductase, an iron-sulfur flavoprotein
34. [4Fe-4S] cluster-depleted Azotobacter vinelandii ferredoxin-I: A new 3Fe iron-sulfur protein
35. 4] clusters (M = Zn, Co, Mn) in Pyrococcus furiosus ferredoxin
36. 4] cluster in Desulfovibrio gigas ferredoxin II
37. Atomically defined mechanism for electron-coupled proton transfer to a buried redox centre in a protein
38. Spectroscopic characterization of the novel iron-sulfur cluster in Pyrococcus furiosus ferredoxin
39. 1H-NMR investigation of the electronic and molecular structure of the 4Fe cluster ferredoxin from the hyperthermophile Pyrococcus furiosus - Identification of asp-14 as a cluster ligand in each of the four redox states
40. Effect of iron-sulfur cluster environment in modulating the thermodynamic properties and biological function of ferredoxin from Pyrococcus furiosus