Multiple pathways governing Cdx1 expression during murine development

Developmental Biology

Volumn 239, Issue 2, 2001, Pages 257-269

  Prinos, Panagiotis ^a   Joseph, Suman ^a   Oh, Karen ^a   Meyer, Barbara I ^b   Gruss, Peter ^b   Lohnes, David ^a,c,d  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

Caudal; Cdx; Hox; Retinoic acid receptor; Vertebral specification; Wnt3a

Indexed keywords

HOMEODOMAIN PROTEIN; HOX PROTEIN; PROTEIN CAUDAL; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOID; TRANSCRIPTION FACTOR CDX1; UNCLASSIFIED DRUG; WNT3A PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOREGULATION; CONTROLLED STUDY; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; GENE EXPRESSION REGULATION; GENE LOCUS; HOMEOBOX; IN SITU HYBRIDIZATION; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

MAMMALIA; MURINAE;

EID: 0035891072     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2001.0446     Document Type: Article

References (69)

1. Neural patterning in the vertebrate embryo
2. Expression of Cdx-2 in the mouse embryo and placenta: Possible role in patterning of the extra-embryonic membranes
3. Linking colorectal cancer to Wnt signaling
4. Differentiation requires continuous active control
5. A beta-catenin/XTCF-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus
6. Wnt signaling: A common theme in animal development
7. Transducing positional information to the Hox genes: Critical interaction of cdx gene products with position-sensitive regulatory elements
8. Homeosis and intestinal tumours in Cdx2 mutant mice
9. TCF/LEF factor earn their wings
10. CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling
11. Initiation, establishment and maintenance of Hox gene expression patterns in the mouse
12. Cross-regulation of β-catenin-LEF/TCF and retinoid signaling pathways
13. Patterning of the embryo along the anterior-posterior axis: The role of the caudal genes
14. Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila
15. The Cdx-1 and Cdx-2 homeobox genes in the intestine
16. Wnt3a-/-like phenotype and limb deficiency in LEF1(-/-)TCF1(-/-) mice
17. Murine Cdx-4 bears striking similarities to the Drosophila caudal gene in its homeodomain sequence and early expression pattern
18. The coregulator exchange in transcriptional functions of nuclear receptors
19. Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development
20. Retinoids and vertebrate development
21. Curbing the nuclear activities of β-catenin. Control over Wnt target gene expression
22. The p300/CBP acetyltransferases function as transcriptional coactivators of β-catenin in vertebrates
23. Expression of a Delta homologue in prospective neurons in the chick
24. The Wnt signaling pathway
25. The Caenorhabditis elegans APC-related gene apr-1 is required for epithelial cell migration and Hox gene expression
26. Gene splicing by overlap extension
27. Retinoic acid regulation of Cdx1: An indirect mechanism for retinoids and vertebral specification
28. Isolation and characterization of the murine homeobox gene Cdx-1. Regulation of expression in intestinal epithelial cells
29. Hox gene expression in a single Caenorhabditis elegans cell is regulated by a caudal homolog and intercellular signals that inhibit wnt signaling
30. Wnt signaling from the dorsal neural tube is required for the formation of the medial dermomyotome
31. Wnt-3a is required for somite specification along the anteroposterior axis of the mouse embryo and for regulation of cdx-1 expression
32. Regulation of Hox gene expression and posterior development by the Xenopus caudal homologue Xcad3
33. A molecular basis for retinoic acid-induced axial truncation
34. Structure of the murine homeobox gene cdx-2. Expression in embryonic and adult intestinal epithelium
35. Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid
36. Hox genes in vertebrate development
37. Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-β and Wnt pathways
38. Identification of a retinoic acid responsive enhancer 3′ of the murine homeobox gene Hox-1.6
39. Retinoic acid-responsive enhancers located 3′ of the Hox A and Hox B homeobox gene clusters. Functional analysis
40. Wnt/β-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine
41. A molecular gradient in early Drosophila embryos and its role in specifying the body pattern
42. The chicken caudal genes establish an anterior-posterior gradient by partially overlapping temporal and spatial patterns of expression
43. A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1
44. Mouse Cdx-1 expression during gastrulation
45. 2+ pathways
46. Activation of beta-catenin-TCF signaling in colon cancer by mutations in beta-catenin or APC
47. Splicing and polyadenylylation at cryptic sites in RNA transcribed from pSV2-neo
48. Expression of the murine Hoxa4 gene requires both autoregulation and a conserved retinoic acid response element
49. Nested expression and sequential downregulation of the Xenopus caudal genes along the anterior-posterior axis
50. Wnt signaling and cancer
51. Identification of a retinoic acid response element upstream of the murine Hox-4.2 gene
52. eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus
53. LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic
54. Expression of a retinoic acid response element-hsplacz transgene defines specific domains of transcriptional activity during mouse embryogenesis
55. Ectodermal patterning in vertebrate embryos
56. Cytoskeletal reorganization by soluble Wnt-3a protein signaling
57. Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes
58. A homeodomain protein related to caudal regulates intestine-specific gene transcription
59. Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid
60. Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein
61. Wnt-3a regulates somite and tailbud formation in the mouse embryo
62. Activation of enhancer elements by the homeobox gene Cdx2 is cell line specific
63. The C-terminal transactivation domain of beta-catenin is necessary and sufficient for signaling by the LEF-1/beta-catenin complex in Xenopus laevis
64. Mechanisms of Wnt signaling in development
65. Cell type-specific autoregulation of the Caudal-related homeobox gene Cdx-2/3
66. T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification
67. A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene