Identification of an octamer element required for in vivo expression of the TIE1 gene in endothelial cells

Biochemical Journal

Volumn 360, Issue 1, 2001, Pages 23-29

  Boutet, S C ^a   Quertermous, T ^a   Fadel, B M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Angiogenesis; Transcription; Vascular development

Indexed keywords

CELLS; DNA; GENES; PROTEINS;

OCTAMER ELEMENTS;

BIOCHEMISTRY;

ANGIOPOIETIN RECEPTOR; GENE PRODUCT; TIE 1 RECEPTOR; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; EMBRYO; EMBRYO CULTURE; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; BETA-GALACTOSIDASE; CELLS, CULTURED; DNA; ENDOTHELIUM; GENOTYPE; MICE; MICE, TRANSGENIC; MUTATION; POINT MUTATION; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, TIE-1; RECEPTORS, CELL SURFACE; RECEPTORS, TIE; TRANSCRIPTION, GENETIC; TRANSFECTION; TRANSGENES;

ANIMALIA; MUS MUSCULUS;

EID: 0035890667     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3600023     Document Type: Article

References (22)

1. Signaling vascular morphogenesis and maintenance
2. Mechanisms of angiogenesis
3. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
4. The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells
5. Cell autonomous functions of the receptor tyrosine kinase TIE in a late phase of angiogenic capillary growth and endothelial cell survival during murine development
6. Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
7. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
8. Vascular endothelial cell lineage-specific promoter in transgenic mice
9. Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice
10. Octamer-dependent in vivo expression of the endothelial cell-specific TIE2 gene
11. Endothelial-specific gene expression directed by the tie gene promoter in vivo
12. Role of ets factors in the activity and endothelial cell specificity of the mouse Tie gene promoter
13. Vascularization of the mouse embryo: A study of flk-1, tek, tie, and vascular endothelial growth factor expression during development
14. Introduction of DNA into mammalian cells
15. Functional analysis of the endothelial cell-specific tie2/tek promoter identifies unique protein binding elements
16. Rapid test for in vivo stability and DNA binding of mutated octamer binding proteins with 'mini-extracts' prepared from transfected cells
17. Identification of vascular endothelial growth factor (VEGF) receptor-2 (Flk-1) promoter/enhancer sequences sufficient for angioblast and endothelial cell-specific transcription in transgenic mice
18. Structure of the 5′ ends of immunoglobulin genes: A novel conserved sequence
19. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins
20. A B-cell coactivator of octamer-binding transcription factors
21. Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B