Hydrolytic degradation of poly(carbonate)-urethanes by monocyte-derived macrophages

Biomaterials

Volumn 22, Issue 22, 2001, Pages 3025-3033

  Labow, R S ^a   Meek, E ^a   Santerre, J P ^b  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Biodegradation; Hydrolytic activities; Monocyte derived macrophages; Oxidation; Polyurethane

Indexed keywords

CHOLESTEROL; HYDROLYSIS; OXIDATION; PROTEINS;

MACROPHAGES;

DEGRADATION;

BENZYLSULFONYL FLUORIDE; CYCLOHEXIMIDE; ESTERASE; POLYCARBONATE; POLYURETHAN;

ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; HUMAN; HUMAN CELL; HYDROLYSIS; MACROPHAGE; MATERIALS; MONOCYTE; OXIDATION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY;

BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; CELLS, CULTURED; HUMANS; HYDROLYSIS; MACROPHAGES; MATERIALS TESTING; MICROSCOPY, ELECTRON, SCANNING; MONOCYTES; OXIDATION-REDUCTION; POLYMERS; POLYURETHANES; SURFACE PROPERTIES;

EID: 0035889832     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(01)00049-7     Document Type: Article

References (36)

1. Polyurethane elastomer biostability
2. A review of the biostability and carcinogenicity of polyurethanes in medicine and the new generation of 'biostable' polyurethanes
3. Mechanisms of inflammation and infection with implanted devices
4. Degradation of biomaterials by phagocyte-induced oxidants
5. In vitro modulation of macrophage phenotype and inhibition of polymer degradation by dexamethasone in a human macrophage/Fe/stress system
6. Effect of pharmacologic agents on release of lysosomal enzymes from alveolar mononuclear cells
7. Theoretical analysis of in vivo macrophage adhesion and foreign body giant cell formation on strained poly(etherurethane urea) elastomers
8. Effect of biomaterial surface charge on the inflammatory response; evaluation of cellular infiltration and TNF alpha production
9. Differential synthesis of cholesterol esterase by monocyte-derived macrophages cultured on poly(ether and ester-)urethanes
10. Model systems to assess the destructive potential of neutrophils and monocyte-derived macrophages during the acute and chronic phases of inflammation
11. Biodegradation evaluation of polyether and polyester-urethanes with oxidative and hydrolytic enzymes
12. The enzymatic hydrolysis of a synthetic biomembrane; a new substrate for cholesterol and carboxyl esterase
13. Enzyme-biomaterial interactions; effect of biosystems on degradation of polyurethanes
14. The effect of hard segment size on the hydrolytic stability polyether-urea-urethanes when exposed to cholesterol esterase
15. Biodegradation of commercial dental composites by cholesterol esterase
16. Macrophage colony-stimulating factor regulates both activities of neutral and acidic cholesteryl ester hydrolases in human monocyte-derived macrophages
17. Neutrophil-mediated degradation of segmented polyurethanes
18. Biodegradation of a poly(ester-urea-urethane) by cholesterol esterase; isolation and identification of principal degradation products
19. Isolation of mononuclear cells and granulocytes from human blood
20. Rapid fluorometric quantification of monocyte attachment in tissue culture wells
21. A simple rapid and sensitive DNA assay procedure
22. A quick method for purifying bile salt-activated lipases
23. Synergistic effects of oxidative environments and mechanical stress on in vitro stability of polyetherurethanes and polycarbonateurethanes
24. Chlorination of taurine by human neutrophils
25. Polyurethane vascular prosthesis decreases neointimal formation compared with expanded polytetrafluoroethylene
26. Histology and electron microscopy of explanted bifurcated endovascular aortic grafts; evidence of early incorporation and healing
27. Totally implantable artificial hearts and left ventricular assist devices; selecting impermeable polycarbonate urethane to manufacture ventricles
28. Chemical stability of polyether urethanes versus polycarbonate urethanes
29. In vivo biocompatibility and biostability of modified polyurethanes
30. Regulation of human neutrophil degranulation by LY-83583 and L-arginine; role of cGMP-dependent protein kinase
31. Cellular interactions with biomaterials; in vivo cracking of pre-stressed Pellethane 2363-80A
32. Oxidative biodegradation mechanisms of biaxially strained poly(etherurethane urea) elastomers
33. Neutrophil-mediated biodegradation of medical implant materials