Possible relationship between the van der woude syndrome (vWS) locus and nonsyndromic cleft lip with or without cleft palate (NSCL/P)

American Journal of Medical Genetics

Volumn 104, Issue 1, 2001, Pages 86-92

  Houdayer, Claude ^a,d   Bonaïti Pellié, Catherine ^b,c   Erguy, Caroline ^a   Soupre, Véronique ^a   Dondon, Marie Gabrielle ^b   Bürglen, Lydie ^a   Cougoureux, Emmanuel ^a   Couderc, Rémy ^a   Vazquez, Marie Paule ^a   Bahuau, Michel ^a  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c Service de Biochimie et Biologie Moléculaire   (France)

^d ARMAND TROUSSEAU HOSPITAL   (France)

Author keywords

Linkage Analysis; Nonsyndromic Cleft Lip with or without Cleft Palate (NSCL P); Transmission Disequilibrium test (TDT); Van der Woude Syndrome

Indexed keywords

MICROSATELLITE DNA;

ARTICLE; AUTOSOMAL DOMINANT DISORDER; CLEFT LIP; CLEFT PALATE; CLINICAL FEATURE; CONGENITAL MALFORMATION; FAMILIAL DISEASE; FEMALE; GENE LOCUS; GENETIC LINKAGE; HUMAN; INHERITANCE; MAJOR CLINICAL STUDY; MALE; MULTIGENE FAMILY; PREVALENCE; PRIORITY JOURNAL; VAN DER WOUDE SYNDROME;

ALLELES; CLEFT LIP; CLEFT PALATE; FEMALE; GENOTYPE; HETEROZYGOTE; HUMANS; JAW ABNORMALITIES; LINKAGE DISEQUILIBRIUM; LOD SCORE; MALE; MICROSATELLITE REPEATS; PEDIGREE;

EID: 0035889326     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-8628(20011115)104:1<86::AID-AJMG10053>3.0.CO;2-E     Document Type: Article

References (37)

1. Association of genetic variation of the transforming growth factor-alpha gene with cleft lip and palate
2. Confirmation of linkage of Van der Woude syndrome to chromosome 1q32: Evidence of association with STR alleles suggests possible unique origin of disease mutation
3. Statistical properties of the allelic and genotypic transmission/disequilibrium tests for multiallelic markers
4. Lip pits and deletion 1q32→41
5. Strategies based on marker information for the study of human diseases
6. RET in human development and oncogenesis
7. Evidence, from family studies, for linkage disequilibrium between TGFA and a gene for nonsyndromic cleft lip with or without cleft palate
8. The genetics of cleft lip and cleft palate
9. Van der Woude syndrome (cleft lippalate and paramedian sinuses of the lower lip)
10. A single-nucleotide polymorphic variant of the RET proto-oncogene is underrepresented in sporadic Hirschsprung disease
11. The 1993-1994 Généthon human genetic linkage map
12. Van der Woude syndrome and nonsyndromic cleft lip and palate
13. Orofacial cleft defects: Inference from nature and nurture
14. 1q32-q41 microdeletion with reference to van der Woude syndrome and allied clefting entities
15. Easy calculations of lod scores and genetic risks on small computers
16. Poplyteal pterygium syndrome: A clinical study of three families and report of linkage to the Van der Woude syndrome locus on 1q32
17. Application of transmission disequilibrium tests to nonsyndromic oral clefts: Including candidate genes and environmental exposures in the models
18. Transforming growth factor alpha locus and nonsyndromic cleft lip with or without cleft palate: A reappraisal
19. Linkage of an autosomal dominant clefting syndrome (Van der Woude) to loci on chromosome 1q
20. Identification of susceptibility loci for nonsyndromic cleft lip with or without cleft palate in a two stage genome scan of affected sib-pairs
21. Candidate genes for nonsyndromic cleft lip and palate and maternal cigarette smoking and alcohol consumption: Evaluation of genotype-environment interactions from a population-based case control study of orofacial cleft
22. Evidence for a microdeletion in 1q32-q41 involving the gene responsible for Van der Woude syndrome
23. Microsatellite-based fine mapping of the Van der Woude syndrome locus to an interval of 4.1 cM between D1S245 and D1S414
24. General score tests for associations of genetic markers with disease using cases and their parents
25. Refinement of the Van der Woude gene location and construction of a 3.5-Mb YAC contig and STS map spanning the critical region in 1996 1q32-q41
26. Microdeletions at chromosome bands 1q32-q41 as a cause of van der Woude syndrome
27. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci
28. Further evidence of a relationship between the retinoic acid receptor alpha locus and nonsyndromic cleft lip with or without cleft palate (CL ± P)
29. Variable expression of the poplyteal pterygium syndrome in two 3-generation families
30. The TDT and other family-based tests for linkage disequilibrium and association
31. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
32. The detection of linkage disequilibrium between closely linked markers: RFLPs at the AI-CIII apolipoprotein genes
33. Fistula labii inferioris congenita and its association with cleft lip and palate
34. Exclusion of candidate genes from a role in cleft lip with or without cleft palate: Linkage and association studies
35. Linkage analysis of candidate regions in Swedish nonsyndromic cleft lip with or without cleft palate families
36. Genetic heterogeneity and exclusion of a modifying locus at 17p11.2-p11.1 in Finnish families with van der Woude syndrome
37. Evidence for an association between markers on chromosome 19q and nonsyndromic cleft lip with or without cleft palate in two groups of multiplex families