BCR-ABL transcripts may be detected in essential thrombocythemia but lack clinical significance [5]

Blood

Volumn 98, Issue 6, 2001, Pages 1990-

  Heller, Paula ^a   Komblihtt, Laura I ^a   Cuello, Maria T ^a   Larripa, Irene ^a   Najfeld, Vesna ^a   Molinas, Felisa C ^a  

^a Instituto de Investigaciones Metabolicas   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ANAGRELIDE; BCR ABL PROTEIN; HYDROXYUREA;

ADULT; AGED; BLAST CELL CRISIS; BONE MARROW; CELL STRAIN K 562; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; HUMAN; LETTER; MALE; MYELOFIBROSIS; MYELOID METAPLASIA; PHILADELPHIA 1 CHROMOSOME; POLYCYTHEMIA VERA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENTIAL ANALYSIS; THROMBOCYTHEMIA;

EID: 0035885958     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V98.6.1990     Document Type: Letter

References (8)

1. Emilia G, Marasca R, Zucchini P, et al. BCR-ABL rearrangement is not detectable in essential thrombocythemia [letter]. Blood. 2001;97:2187-2189.
2. Kawasaki ES, Clark SS, Coyne M, et al. Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro. Proc Natl Acad Sci USA. 1988;85:5698-5702.
3. Cross NCP, Hughes TP, Feng L, et al. Minimal residual disease after allogenic bone marrow transplantation for chronic myeloid leukemia in first chronic phase: correlations with acute graft-versus-host disease and relapse. Br J Haematol. 1993;84:67-74.
4. Lampert CL, Kafko M, Scalise A, Najfeld V. The value of interphase fluorescence in situ hibridization in the study of patients with lymphoproliferative disorders: further evidence for a higher sensitivity for detecting chromosome 7 and 8 aneuploidy. Cancer Genet Cytogenet. 1998;105:193-197.
5. Blickstein D, Aviram A, Luboshitz J, et al. Bcr-abl transcripts in bone marrow aspirates of Philadelphia negative essential thrombocythemia patients: clinical presentation. Blood. 1997;90:2768-2771.
6. Singer IO, Sproul A, Tait RC, Soutar R, Gibson B. BCR-ABL transcripts detectable in all myeloproliferative states [abstract]. Blood. 1998;92:427a.
7. Hackwell S, Ross F, Cullis JO. Patients with Essential Thrombocythemia do not express bcr-abl transcripts [letter]. Blood. 1999;93:2420.
8. Stoll DB, Peterson P, Exten R et al. Clinical presentation and natural history of patients with essential thrombocythemia and the Philadelphia chromosome. Am J Hematol. 1988;27:77-83.