Comparative genomic analysis of genes encoding translation elongation factor 1Bα in human and mouse shows EEF1B1 to be a recent retrotransposition event

Genomics

Volumn 77, Issue 3, 2001, Pages 145-148

  Chambers, Doreen M ^a   Rouleau, Guy A ^b   Abbott, Catherine M ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

ALS2; Amyotrophic lateral sclerosis; Eef1b; EEF1B; Elongation; Gene mapping; Paralogue; Pseudogene; Translation

Indexed keywords

ELONGATION FACTOR; TRANSLATION ELONGATION FACTOR 1BALPHA; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN TISSUE; CHROMOSOME 1; CHROMOSOME 2Q; COMPARATIVE GENOMIC HYBRIDIZATION; EXON; GENE EXPRESSION; GENE LOCUS; GENE MAPPING; GENE STRUCTURE; HUMAN; INTRON; MOUSE; MUSCLE TISSUE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PSEUDOGENE; RETROPOSON;

EID: 0035880390     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.2001.6626     Document Type: Article

References (10)

1. Assignment of human elongation factor 1α genes: EEF1A maps to chromosome 6q14 and EEF1A2 to 20q13.3
2. Elongation factor 1 α, translation and the cytoskeleton
3. The lethal mutation of the mouse wasted (wst) is a deletion which abolishes expression of a tissue-specific isoform of translation elongation factor 1α, encoded by the Eef1a2 gene
4. Human elongation factor EF-1 β: Cloning and characterisation of the EF1 β 5a gene and assigment of EF-1 β isoforms to chromosomes 2, 5, 15 and X
5. Nucleotide sequence of human elongation factor-1 β cDNA
6. Human elongation factor 1 β: cDNA and derived amino acid sequence
7. Maps from two interspecific backcross DNA panels available as a community genetic mapping resource
8. Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33-q35
9. A yeast artificial chromosome-based physical map of the juvenile amyotrophic lateral sclerosis (ALS2) critical region on human chromosome 2q33-q34
10. A set of highly conserved RNA-binding proteins, αCP-1 and αCP-2, implicated in mRNA stabilization, are coexpressed from an intronless gene and its intron-containing paralog