Over-expression of cyclin a is highly associated with early relapse and reduced survival in patients with primary breast carcinomas

International Journal of Cancer

Volumn 93, Issue 2, 2001, Pages 283-287

  Bukholm, Ida R K ^a   Bukholm, Geir ^a   Nesland, Jahn M ^b  

^a AKERSHUS UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Breast cancer; Cyclin; Metastases; Norway; Survival

Indexed keywords

CYCLIN A; CYCLIN D3; CYCLIN DEPENDENT KINASE;

ARTICLE; BREAST CARCINOMA; CANCER RECURRENCE; CANCER SURVIVAL; CARCINOGENESIS; CELL CYCLE; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; METASTASIS; MULTIVARIATE ANALYSIS; NORWAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCORING SYSTEM;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CYCLIN A; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; PROGNOSIS; RECURRENCE; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 0035879885     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.1311     Document Type: Article

References (28)

1. Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia
2. The retinoblastoma protein and cell cycle control
3. 1/S phase transition by expression of cyclin D1 and E with an inducible system
4. 1 in mammalian fibroblasts
5. 1 to complete the cell cycle
6. 1-to-S transition
7. 1
8. Cyclin E is required in S phase in normal epithelial cells
9. Functional role of E2F in cell cycle regulation
10. Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
11. Cyclins and oncogenesis
12. 2-M transition are controlled by different cdc2 proteins in higher eukaryotes
13. Cyclin E is required at two points in the human cell cyle
14. Cyclins and cancer
15. Genetic alterations of cyclins, cyclin-dependent kinases and Cdk inhibitors in human cancer
16. The retinobastoma pathway in cell cycle control and cancer
17. Cyclin D1 and retinoblastoma susceptibility gene alterations in non-small lung cancer
18. Oncogenic activation of cyclin A
19. E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
20. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: Experience from a large study with long-term follow-up
21. The expression of cyclin Ds in relation to p53 status in human breast carcinomas
22. Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport
23. 1 cyclins
24. 2 checkpoint function precedes human cell immortalization
25. Study of the cell cycle-dependent assembly of the DNA pre-replication centres in Xenopus egg extracts
26. 2/M are over-expressed in aneuploid mammary carcinomas
27. Cyclin E overexpression, a negative prognostic factor in breast cancer with a strong correlation to oestrogen receptor status
28. Expression of cell-cycle regulators p27 kip1 and cyclin E alone and in combination, correlate with survival in young breast cancer patients