Use of odds ratio or relative risk to measure a treatment effect in clinical trials with multiple correlated binary outcomes: Data from the NINDS t-PA stroke trial

Statistics in Medicine

Volumn 20, Issue 13, 2001, Pages 1891-1901

  Lu, Mei ^a   Tilley, Barbara C ^b  

^a HENRY FORD HEALTH SCIENCES CENTER   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION FUNCTION; COVARIANCE; MATHEMATICAL COMPUTING; RISK ASSESSMENT; STROKE; TREATMENT OUTCOME;

CEREBROVASCULAR ACCIDENT; DRUG EVALUATION; HUMANS; LOGISTIC MODELS; NATIONAL INSTITUTES OF HEALTH (U.S.); ODDS RATIO; RANDOMIZED CONTROLLED TRIALS; RISK; TISSUE PLASMINOGEN ACTIVATOR; TREATMENT OUTCOME; UNITED STATES;

EID: 0035879635     PISSN: 02776715     EISSN: None     Source Type: Journal    
DOI: 10.1002/sim.841     Document Type: Article

References (39)

1. Global tests for multiple binary outcomes
2. Procedures for comparing samples with multiple endpoints
3. The analysis of multiple endpoints in clinical trials
4. Longitudinal data analysis for discrete and continuous outcomes
5. Correlated binary regression with covariates specific to each binary observation
6. Generalized estimation equations for correlated binary data: Using the odds as a measure of association
7. Clinically useful measures of effect in binary analyses of randomized trials
8. Meta-analysis in clinical trials
9. Binomial regression in GLIM: Estimation risk ratios and risk differences
10. Proportion of disease caused or prevented by a given exposure, trait, or intervention
11. Elementary methods of cohort analysis
12. Statistical aspects of the analysis of data from retrospective studies of disease
13. Quasi-likelihood functions, generalized linear models, and the Gauss-Newton method
14. Longitudinal data analysis using generalized linear models
15. A comparison of the generalized estimating equation approach with the maximum likelihood approach for repeated measurements
16. Efficiency and power of tests for multiple binary outcomes
17. Adenosine myocardial protection: Preliminary results of a phase II clinical trial
18. Incidence and determinants for mortality and cardiovascular events in diabetes
19. Use of a global test for multiple outcomes in stroke trials with application to the National Institute of Neurological Disorders and Stroke t-PA Stroke Trial
20. On the criterion that a given system of deviations from the probable in the case of a correlated system of variables is such that it can be reasonably supposed to have arisen from random sampling
21. 2 test of goodness of fit
22. 2 test
23. On chi-square goodness-of-fit tests for continuous distributions
24. 2 test of goodness of fit when expected frequencies are small
25. A general method for approximating to the distribution of likelihood ratio criteria
26. Tables of percentage points of Pearson's goodness-of-fit statistic for use with small expectations
27. 2 for equiprobable multinomials
28. Some covariance models for longitudinal count data with overdispersion
29. Quasi-likelihood and optimal estimation
30. Tissue plasminogen activator for acute ischemic stroke
31. The analysis of multiple correlated binary outcomes: Application to rodent teratology experiments