Biochemical characterization of a novel hypoxanthine/xanthine dNTP pyrophosphatase from Methanococcus jannaschii

Nucleic Acids Research

Volumn 29, Issue 14, 2001, Pages 3099-3107

  Chung, Ji Hyung ^a,b   Back, Jung Ho ^a,b   Park, Young In ^b   Han, Ye Sun ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYADENOSINE TRIPHOSPHATE; DNA; DNA DIRECTED DNA POLYMERASE BETA; ENDONUCLEASE; EXONUCLEASE; HYPOXANTHINE; INOSINE TRIPHOSPHATE; NUCLEOSIDE TRIPHOSPHATE; NUCLEOTIDE; NUCLEOTIDE PYROPHOSPHATASE; UNCLASSIFIED DRUG; XANTHINE; XANTHOSINE TRIPHOSPHATE;

ANIMAL CELL; ARCHAEOGLOBUS FULGIDUS; ARTICLE; BIOCHEMISTRY; CATALYSIS; CONTROLLED STUDY; DNA TEMPLATE; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE INSERTION; GENE MUTATION; HYDROLYSIS; METHANOCOCCUS JANNASCHII; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEIN PURIFICATION; SEQUENCE HOMOLOGY;

ANIMALIA; ARCHAEOGLOBUS FULGIDUS; ESCHERICHIA COLI; METHANOCALDOCOCCUS JANNASCHII; METHANOCOCCUS; METHANOCOCCUS JANNASCHII; NEGIBACTERIA;

EID: 0035879027     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.14.3099     Document Type: Article

References (48)

1. The reaction of ribonucleosides with nitrous acid. Side products and kinetics
2. DNA glycosylases, endonucleases for apurinic/apyrimidinic sites and base excision-repair
3. The reaction of nitrous acid with deoxyribonucleic acid
4. Site-specific mutagenesis in vivo by single methylated or deaminated purine bases
5. Hypoxanthine in deoxyribonucleic acid: Generation by heat-induced hydrolysis of adenine residues and release in free form by a deoxyribonucleic acid glycosylase from calf thymus
6. Further characterization of Escherichia coli endonuclease V
7. Deoxyxanthosine in DNA is repaired by Escherichia coli endonuclease V
8. DNA glycosylases
9. Substrate specificity of human methylpurine DNA N-glycosylase
10. Interactions of the human, rat,S. cerevisiae and E. coli 3-methyladenine DNA glycosylases with DNA containing dIMP residues
11. Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis
12. Genetic studies of human erythrocyte inosine triphosphatase
13. Purine metabolism in normal and ITP-pyrophosphohydrolase-deficient human erythrocytes
14. Human inosine triphosphatase: Catalytic properties and population studies
15. The distribution of nucleoside triphosphate pyrophosphohydrolase in the tissues of the rabbit
16. Inosine triphosphate pyrophosphohydrolase deficiency in a kindred with adenosine deaminase deficiency
17. Metabolism of dITP in HeLa cell extracts, incorporation into DNA by isolated nucleic and release of hypoxanthine from DNA by a hypoxanthine-DNA glycosylase activity
18. Structure-based identification of a novel NTPase from Methanococcus jannaschii
19. MutT prevents leakiness
20. MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis
21. Human dUTP pyrophosphatase: cDNA sequence and potential biological importance of the enzyme
22. dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiae
23. Kinetic characterization of dUTPase from Escherichia coli
24. Synthesis and metabolism of uracil-containing deoxyribonucleic acid in Escherichia coli
25. Formation of okazaki pieces at the Escherichia coli replication fork in vitro
26. Purification and characterization of a novel deoxyinosine-specific enzyme, deoxyinosine 3′-endonuclease, from Escherichia coli
27. Biochemical studies on the mutagen, 6-N-hydroxylaminopurine
28. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of dye-binding
29. The crystal structure of a hyperthermophilic archaeal TATA-box binding protein
30. Glutamate dehydrogenase from the hyperthermophilic Pyrococcus furiosus: Thermal denaturation and activation
31. Enzymatic excision of free hypoxanthine from polydeoxynucleotides and DNA containing deoxyinosine monophosphate residues
32. Induction of mutation of a synthetic c-Ha-ras gene containing hypoxanthine
33. 2-Aminopurine
34. Induction of gene mutation in and cell transformation of mammalian cells by modified purines: 2-aminopurine and 6-N-hydroxylaminopurine
35. Transversion-specific purine analogue mutagens and the mechanism of hydroxylaminopurine mutagenesis
36. Base analog 6-N-hydroxylaminopurine mutagenesis in the yeast Saccharomyces cerevisiae is controlled by replicative DNA polymerases
37. The conformational variability of an adenosine-inosine base pair in a synthetic DNA dodecamer
38. NMR studies for identification of dI:dG mismatch base-pairing structure in DNA
39. Identification of I:A mismatch base-pairing structure in DNA
40. Polynucleotide analogues. IX. Poly-xanthylic acid
41. Identification of the altered bases in mutated single-stranded DNA. IV. Nitrous acid induction of the transitions guanine to adenine and thymine to cytosine
42. Synthesis and properties of oligonucleotides containing 2′-deoxynebularine and 2′-deoxyanthosine
43. In vitro replication study of modified bases in ras sequence
44. Endonuclease V protects Escherichia coli against specific mutations caused by nitrous acid
45. The role of the mutT gene of Escherichia coli in maintaining replication fidelity
46. Structure/function analysis of a dUTPase: Catalytic mechanism of a potential chemotherapeutic target