Is myosin phosphatase regulated in vivo by inhibitor-1? Evidence from inhibitor-1 knockout mice

Journal of Physiology

Volumn 534, Issue 2, 2001, Pages 357-366

  Carr, Andrew N ^a   Sutliff, Roy L ^b   Weber, Craig S ^b   Allen, Patrick B ^c   Greengard, Paul ^c   De Lanerolle, Primal ^d   Kranias, Evangelia G ^a   Paul, Richard J ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; ISOPRENALINE; MYOSIN; MYOSIN LIGHT CHAIN; PHENYLEPHRINE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PHOSPHORUS 32; POTASSIUM CHLORIDE; TISSUE EXTRACT;

ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME ACTIVITY; ENZYME REGULATION; IN VIVO STUDY; KNOCKOUT MOUSE; MODULATION; MOUSE; MUSCLE FUNCTION; MUSCLE ISOMETRIC CONTRACTION; MUSCLE RELAXATION; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN PHOSPHORYLATION; SENSITIZATION; SMOOTH MUSCLE; SMOOTH MUSCLE CONTRACTILITY;

ACETYLCHOLINE; ANIMALS; AORTA; CALCIUM; CARRIER PROTEINS; FORSKOLIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN PHOSPHATASE; NITROPRUSSIDE; PHENYLEPHRINE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PORTAL VEIN; POTASSIUM CHLORIDE; RECEPTORS, ADRENERGIC, BETA; RNA-BINDING PROTEINS; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 0035878745     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2001.00357.x     Document Type: Article

References (37)

1. The control of protein phosphatase-1 by targetting subunits. The major myosin phosphatase in avian smooth muscle is a novel form of protein phosphatase-1
2. Protein phosphatase-1 regulation in the induction of long-term potentiation: Heterogeneous molecular mechanisms
3. The structure and regulation of protein phosphatases
4. The relationship between calmodulin binding and phosphorylation of smooth muscle myosin kinase by the catalytic subunit of 3':5' cAMP-dependent protein kinase
5. Myosin phosphorylation/dephosphorylation and regulation of airway smooth muscle contractility
6. Molecular cloning of protein phosphatase inhibitor-1 and its expression in rat and rabbit tissues
7. Dephosphorylation of distinct sites in myosin light chain by two types of phosphatase in aortic smooth muscle
8. Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase
9. 2+ sensitization of skinned muscle of guinea pig vas deferens
10. Myosin light chain kinases
11. Arachidonic acid and diacylglycerol release associated with inhibition of myosin light chain dephosphorylation in rabbit smooth muscle
12. Myosin phosphatase: Subunits and interactions
13. Myosin light chain phosphatase: Subunit composition, interactions and regulation
14. DARPP-32, a dopamine- and adenosine 3′:5′-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1
15. Separation and characterization of two phosphorylase phosphatase inhibitors from rabbit skeletal muscle
16. Regulation of protein phosphatase-1G from rabbit skeletal muscle. 2. Catalytic subunit translocation is a mechanism for reversible inhibition of activity toward glycogen-bound substrates
17. Interactions and properties of smooth muscle myosin phosphatase
18. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
19. Targeted ablation of the phospholamban gene is associated with a marked decrease in sensitivity in aortic smooth muscle
20. i homeostasis and cyclic nucleotide relaxation in aorta of phospholamban-deficient mice
21. 2+ desensitization in vascular smooth muscle by activating the myosin light chain phosphatase
22. Possible involvement of the novel CPI-17 protein in protein kinase C signal transduction of rabbit arterial smooth muscle
23. Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban
24. Purification and characterization of smooth muscle myosin-associated phosphatase from chicken gizzards
25. Site-specific dephosphorylation of smooth muscle myosin light chain kinase by protein phosphatases 1 and 2A
26. Physiologic importance of protein phosphatase inhibitors
27. Dephosphorylation of the 20,000-dalton light chain of myosin by two different phosphatases from smooth muscle
28. Inhibitor-1 is not required for the activation of glycogen synthase by insulin in skeletal muscle
29. Purification and characterization of the mammalian myosin light chain phosphatase holoenzyme. The differential effects of the holoenzyme and its subunits on smooth muscle
30. Myosin light chain phosphatase: A Cinderella of cellular signaling
31. 2+ -sensitivity and of the time course of contraction in smooth muscle: A major role of protein phosphatases?
32. Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II
33. Vasorelaxant properties of parathyroid hormone-related protein in the mouse: Evidence for endothelium involvement independent of nitric oxide formation
34. Protein phosphatase composition in the smooth muscle of guinea-pig ileum studied with okadaic acid and inhibitor 2
35. 2+ dependence of smooth muscle contraction
36. Enhancement of smooth muscle contraction with protein phosphatase inhibitor 1: Activation of inhibitor 1 by cGMP-dependent protein kinase
37. Phosphorylation of MYPT1 by protein kinase C attenuates interaction with PP1 catalytic subunit and the 20 kDa light chain of myosin