Sensorimotor demyelinating neuropathy with IgM antibody against gangliosides GD1a, GT1b and GM3

Journal of the Neurological Sciences

Volumn 188, Issue 1-2, 2001, Pages 9-11

  Mizutani, Kotaro ^a,b   Oka, Nobuyuki ^a   Kusunoki, Susumu ^c   Kaji, Ryuji ^a   Mezaki, Takahiro ^a,b   Akiguchi, Ichiro ^a   Shibasaki, Hiroshi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b Sakakibara Hakuho Hospital   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Antiganglioside antibodies; Gangliosides; Myelin associated glycoprotein; Sensorimotor demyelinating neuropathy

Indexed keywords

GANGLIOSIDE GD 1A; GANGLIOSIDE GM3; GANGLIOSIDE GT 1B; IMMUNOGLOBULIN M ANTIBODY; LIGAND; MYELIN ASSOCIATED GLYCOPROTEIN; STEROID;

ACTION POTENTIAL; ADHESION; AGED; ARTICLE; CASE REPORT; CLINICAL FEATURE; DEMYELINATING NEUROPATHY; DEMYELINATION; DISPERSION; HUMAN; MALE; MOTOR NEUROPATHY; MUSCLE WEAKNESS; NERVE CONDUCTION; NERVE FIBER MEMBRANE; PARESTHESIA; PRIORITY JOURNAL; SENSORY NEUROPATHY;

AGED; ANTIBODIES; DEMYELINATING DISEASES; G(M3) GANGLIOSIDE; GANGLIOSIDES; HUMANS; IMMUNOGLOBULIN M; MALE; MOVEMENT; SENSATION;

EID: 0035878568     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(01)00537-8     Document Type: Article

References (13)

1. Frequency and clinical correlates of anti-neural IgM antibodies in neuropathy associated with IgM monoclonal gammopathy
2. Sialic acid specificity of myelin-associated glycoprotein binding
3. Cerebellar ataxia and polyneuropathy in a patient with IgM M-protein specific to the Ga1(β1-3)GalNAc epitope
4. The myelin-associated glycoprotein is enriched in multivesicular bodies and periaxonal membranes of actively myelinating oligodendrocytes
5. Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects
6. Monoclonal IgM in a patient with paraproteinemic polyneuropathy binds to gangliosides containing disialosyl groups
7. Sensory neuropathy associated with monoclonal immunoglobulin M to GD1b ganglioside
8. IgM M-protein in a patient with sensory-dominant neuropathy binds preferentially to polysialogangliosides
9. 2 cold agglutinins
10. IgM M-protein with antibody activity against gangliosides with disialosyl residue in sensory neuropathy binds to sensory neurons
11. Motor neuropathy with activity of monoclonal IgM antibody to GD1a ganglioside
12. Anti-GD1a ganglioside antibodies in peripheral motor syndromes
13. Severe motor-dominant neuropathy with IgM M-protein binding to the NeuAcα2-3Galβ-moiety