Preferred binding sites for [N-MeCys3, N-MeCys7]TANDEM determined using a universal footprinting substrate

Analytical Biochemistry

Volumn 293, Issue 2, 2001, Pages 246-250

  Lavesa, Manuel ^a   Fox, Keith R ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

DNase I; Footprinting; Quinoxaline antibiotic; TANDEM

Indexed keywords

ANTIBIOTICS;

DNASE I; FOOTPRINTING; QUINOXALINES; TANDEM; WEAK INTERACTIONS;

BINDING SITES;

ANTIBIOTIC AGENT; DEOXYRIBONUCLEASE I; DNA; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG; [3 N METHYLCYSTEINE,7 N METHYLCYSTEINE]TANDEM;

ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; DNA BINDING; DNA FOOTPRINTING; DRUG BINDING SITE; DRUG DNA INTERACTION; LIGAND BINDING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

EID: 0035876020     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.2001.5124     Document Type: Article

References (20)

1. DNAase footprinting - Simple method for detection of protein-DNA binding specificity
2. Methidiumpropyl-EDTA: Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNA
3. Sequence-specific binding of echinomycin to DNA: Evidence for conformational changes affecting flanking sequences
4. DNA structural variations produced by actinomycin and distamycin as revealed by DNAase I footprinting
5. Quantitative DNase footprint titration
6. Interaction between synthetic analogues of quinoxaline antibiotics and nucleic acids
7. Sequence preferences in the binding to DNA of triostin A and TANDEM as reported by DNase I footprinting
8. DNA sequence recognition by under-methylated analogues of triostin A
9. 7]TANDEM binds to the dinucleotide TpA
10. 7] TANDEM to TpA
11. 7]TANDEM binding to DNA oligonucleotide
12. 2
13. NMR investigation of Hoogsteen base pairing in quinoxaline antibiotic-DNA complexes
14. 2 complex
15. 7]TANDEM and triostin A to DNA containing a CpI step
16. 7]TANDEM from TpA sites in DNA
17. DNA recognition by quinoxaline antibiotics: Use of base-modified DNA molecules to investigate determinants of sequence-specific binding of triostin A and TANDEM
18. Evidence for sequence preferences in the intercalative binding of ethidium bromide to dinucleoside monophosphates