RecA-mediated strand exchange traverses substitutional heterologies more easily than deletions or insertions

Nucleic Acids Research

Volumn 29, Issue 12, 2001, Pages 2464-2470

  Bucka, A ^a   Stasiak, A ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DNA; RAD51 PROTEIN; RECA PROTEIN;

ARTICLE; ASSAY; BACTERIUM; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND; EUKARYOTE; GENE DELETION; GENE INSERTION; HOLLIDAY JUNCTION; HYDROLYSIS; IN VITRO STUDY; MOLECULAR EVOLUTION; MOLECULAR INTERACTION; MOLECULE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

EID: 0035875531     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.12.2464     Document Type: Article

References (37)

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2. Initiation of genetic recombination and recombination-dependent replication
3. The E. coli RuvAB proteins branch migrate Holliday junctions through heterologous DNA sequences in a reaction facilitated by SSB
4. Homologous recombination proteins in prokaryotes and eukaryotes
5. Role of the human RAD51 protein in homologous recombination and double-stranded-break repair
6. RadA protein is an archaeal RecA protein homolog that catalyzes DNA strand exchange
7. RecA-mediated strand exchange reactions between duplex DNA molecules containing damaged bases, deletions, and insertions
8. Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs
9. Reverse branch migration of Holliday junctions by RecG protein: A new mechanism for resolution of intermediates in recombination and DNA repair
10. RecQ DNA helicase is a suppressor of illegitimate recombination in Escherichia coli
11. RecQ helicase, in concert with RecA and SSB proteins, initiates and disrupts DNA recombination
12. Heteroduplex formation by recA protein: Polarity of strand exchanges
13. Insertions, deletions and mismatches in heteroduplex DNA made by recA protein
14. Torsional stress generated by RecA protein during DNA strand exchange separates strands of a heterologous insert
15. Effect of length and location of heterologous sequences on RecA-mediated strand exchange
16. RecA tests homology at both pairing and strand exchange
17. The ATPase activity of RecA is needed to push the DNA strand exchange through heterologous regions
18. Stable DNA heteroduplex formation catalyzed by the Escherichia coli RecA protein in the absence of ATP hydrolysis
19. Energetics of RecA-mediated recombination reactions. Without ATP hydrolysis RecA can mediate polar strand exchange but is unable to recycle
20. On the role of ATP hydrolysis in RecA protein-mediated DNA strand exchange. I. Bypassing a short heterologous insert in one DNA substrate
21. Stable synapsis of homologous DNA molecules mediated by the Escherichia coli RecA protein involves local exchange of DNA strands
22. Role of RecA protein spiral filaments in genetic recombination
23. Radioprobing of a RecA-three-stranded DNA complex with iodine 125: Evidence for recognition of homology in the major groove of the target duplex
24. The direction of RecA protein assembly onto single-strand DNA is the same as the direction of strand assimilation during strand exchange
25. Formation of a single base mismatch impedes spontaneous DNA branch migration
26. Helical repeat of DNA in the region of homologous pairing
27. The duplex DNA is very underwound in the three-stranded RecA protein-mediated synaptic complex
28. The function of the secondary DNA-binding site of RecA protein during DNA strand exchange
29. Visualization of RecA-DNA complexes involved in consecutive stages of an in vitro strand exchange reaction
30. Electron microscopic visualization of the RecA-mediated pairing and branch migration phases of DNA strand exchange
31. Structure and function of RecA-DNA complexes
32. The RecA hexamer is a structural homologue of ring helicases
33. RecA as a motor protein. Testing models for the role of ATP hydrolysis in DNA strand exchange
34. The helicity of DNA in complexes with recA protein
35. Elongation of duplex DNA by recA protein