Interleukin-2 activates human peripheral blood eosinophils

Cellular Immunology

Volumn 210, Issue 2, 2001, Pages 116-124

  Hoenstein, Ronit ^a   Admon, Dan ^b   Solomon, Abraham ^b   Norris, Alan ^a   Moqbel, Redwan ^c   Levi Schaffer, Francesca ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Eosinophil peroxidase; Eosinophils; Interleukin 2; Interleukin 6; Nedocromil sodium; Platelet activating factor

Indexed keywords

EOSINOPHIL PEROXIDASE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 6; NEDOCROMIL SODIUM; PEROXIDASE; THROMBOCYTE ACTIVATING FACTOR; UNCLASSIFIED DRUG;

ALLERGY; ARTICLE; ATOPY; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EOSINOPHIL; EOSINOPHILIA; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOSTIMULATION; INHIBITION KINETICS; MEDIATOR RELEASE; PERIPHERAL CIRCULATION; PHARMACOLOGICAL STIMULATION; PRIORITY JOURNAL; RECEPTOR BINDING;

EID: 0035874770     PISSN: 00088749     EISSN: None     Source Type: Journal    
DOI: 10.1006/cimm.2001.1808     Document Type: Article

References (46)

1. Eosinophils: Biology and role in disease
2. The eosinophil granule proteins in serum, but not the oxidative metabolism of the blood eosinophils, are increased in cancer
3. Eosinophils and human cancer
4. The role of eosinophils in the pathobiology of Hodgkin's disease
5. Study of eosinophil-endothelial adhesion, production of oxygen radicals and release of eosinophil cationic protein by peripheral blood eosinophils of patients with rheumatoid arthritis
6. Human eosinophils regulate human lung-and skin-derived fibroblast properties in vitro: A role for transforming growth factor β (TGF-β)
7. Release of granule proteins from human eosinophils stimulated with mast- cell mediators
8. Identification of lipoxygenase products from arachidonic acid metabolism in stimulated murine eosinophils
9. Platelet-activating factor-induced human eosinophil activation. Generation and release of cyclooxygenase metabolites in human blood eosinophils from asthmatics
10. Superoxide production by eosinophils: Activation by histamine
11. Cytokines directly induce degranulation and superoxide production from human eosinophils
12. Cytokine generation by eosinophils
13. Effects of IL-5, granulocyte/macrophage colony-stimulating factor (GM-CSF) and IL-3 on the survival of human blood eosinophils in vitro
14. Granulocyte/macrophage colony-stimulating factor (GM-CSF) gene expression by eosinophils in nasal polyposis
15. Synthesis of type 1 (IFN gamma) and type 2 (IL-4, IL-5, and IL-10) cytokines by human eosinophils
16. IL-5 and IL-5 receptor expression on human eosinophils in relation to eosinophil activation
17. Human T-cell precursors: Involvement of the IL-2 pathway in the generation of mature T cells
18. Gene expression of interleukin-2 in purified human peripheral blood eosinophils
19. Identification of interleukin-2 in human peripheral blood eosinophils
20. Human eosinophils express functional interleukin 2 receptors
21. Role of IL-5 in IL-2-induced eosinophilia. In vivo and in vitro expression of IL-5 mRNA by IL-2
22. Human eosinophils from hypereosinophilic patients spontaneously express the p55 but not the p75 interleukin 2 receptor subunit
23. The effect of nedocromil sodium on human airway epithelial cell-induced eosinophil chemotaxis and adherence to human endothelial cell in vitro
24. Inhibition of cytokine-primed eosinophil chemotaxis by nedocromil sodium
25. The effect of human eosinophils on cultured human nasal epithelial cell activity and the influence of nedocromil sodium in vitro
26. Inhibition of neutrophil and eosinophil induced chemotaxis by nedocromil sodium and sodium cromoglycate
27. Effects of nedocromil sodium (Tilade) on the activation of human eosinophils and neutrophils and the release of histamine from mast cells
28. Association of granulocyte-macrophage colony-stimulating factor with the crystaloid granules of human eosinophils
29. Basophils in bronchial asthma with reference to reagin-type allergy
30. A kinetic assay for eosinophil peroxidase activity in eosinophils and eosinophil conditioned media
31. CD11b/CD18 (Mac-1) is required for degranulation of human eosinophils induced by human recombinant granulocyte-macrophage colony-stimulating factor and platelet-activating factor
32. Effect of interleukin-5 and granulocyte-macrophage colony stimulating factor on in vitro eosinophil function: Comparison with airway eosinophils
33. Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3
34. Effects of IFN on human eosinophils in comparison with other cytokines. A novel class of eosinophil activators with delayed onset of action
35. Interferon-gamma induces interleukin-3 release from peripheral blood eosinophils
36. Expression of mRNA and immunoreactivity for the granulocyte/macrophage colony-stimulating factor in activated human eosinophils
37. Cross linking of VLA/CD29 molecule has a co-mitogenic effect with anti-CD 3 on CD4 cell activation in serum free culture system
38. A crucial role for beta 2 integrin in the activation of eosinophils stimulated by IgG
39. Adhesion to fibronectin prolongs eosinophil survival
40. Increased adhesion to vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 of eosinophils from patients with asthma
41. - in response to physiologic soluble stimuli is differentially modulated by extracellular matrix components and endothelial cells
42. Site of action of the antiallergic drugs cromoglycate and doxantrazole [proceedings]
43. Antiallergic drug cromolyn may inhibit histamine secretion by regulating phosphorylation of a mast cell protein
44. Immunologically activated chloride channels involved in degranulation of rat mucosal mast cells
45. Asthma prophylaxis agents alter the function of an airway epithelial chloride channel
46. Nedocromil sodium modulates nonadrenergic, noncholinergic bronchoconstrictor nerves in guinea pig airways in vitro