Alteration of nuclear factor-κB (NF-κB) expression in bone marrow stromal cells treated with etoposide

Biochemical Pharmacology

Volumn 61, Issue 10, 2001, Pages 1243-1252

  Hall, Brett M ^a,b   Fortney, James E ^a   Gibson, Laura F ^a,b  

^a WEST VIRGINIA UNIVERSITY   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Chemotherapy; Hematopoiesis; NF B; Stromal cell; VCAM 1; VP 16

Indexed keywords

DNA; ETOPOSIDE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P50; SYNAPTOTAGMIN; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BONE MARROW CELL; CELL DAMAGE; CELL FUNCTION; CELLULAR DISTRIBUTION; CONSENSUS SEQUENCE; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; DRUG EFFECT; DRUG EXPOSURE; DRUG MECHANISM; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROMA CELL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BONE MARROW; CAPSAICIN; CELL NUCLEUS; CELLS, CULTURED; CONSENSUS SEQUENCE; DNA-BINDING PROTEINS; ETOPOSIDE; GENE EXPRESSION; HUMANS; I-KAPPA B PROTEINS; NF-KAPPA B; NUCLEAR PROTEINS; RNA STABILITY; RNA, MESSENGER; STROMAL CELLS; SUBCELLULAR FRACTIONS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0035873847     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00602-5     Document Type: Article

References (51)

1. Cells and molecules that regulate B lymphopoiesis in bone marrow
2. Regulation of hemopoiesis by bone marrow stromal cells and their products
3. Human B-lymphopoiesis is supported by bone marrow-derived stromal cells
4. The growth response to IL-7 during normal human B cell ontogeny is restricted to B-lineage cells expressing CD34
5. Development of a bone marrow culture for maintenance and growth of normal human B cell precursors
6. Long-term culture of B lymphocytes and their precursors from murine bone marrow
7. Disruption of bone marrow stromal cell function by etoposide
8. + cells
9. Hematopoietic stem cell compartment: Acute and late effects of radiation therapy and chemotherapy
10. Role of bone marrow stromal cells in irradiation leukemogenesis
11. Effects of irradiation of CBA/CA mice on hematopoietic stem cells and stromal cells in long-term bone marrow cultures
12. Reduced expression of vascular cell adhesion molecule-1 on bone marrow stromal cells isolated from marrow transplant recipients correlates with a reduced capacity to support human B lymphopoiesis in vitro
13. Inhibitors of topoisomerase II prevent cytokine-induced expression of vascular cell adhesion molecule-1, while augmenting the expression of endothelial leukocyte adhesion molecule-1 on human umbilical vein endothelial cells
14. Interleukin-1α administered after autologous transplantation: A phase I/II clinical trial
15. Dose-intensive chemotherapy with etoposide-cyclophosphamide for advanced breast cancer
16. Stromal cell associated haemopoiesis
17. The essential cells of the hemopoietic microenvironment
18. Bone marrow connective tissue and the haemopoietic microenvironment
19. Biology of the hemopoietic microenvironment
20. Adhesion receptors as regulators of the hematopoietic process
21. Adhesion receptors on bone marrow stromal cells: In vivo expression of vascular cell adhesion molecule-1 by reticular cells and sinusoidal endothelium in normal and γ-irradiated mice
22. Blood cell precursors in context. Composition of the bone marrow microenvironment that supports B lymphopoiesis
23. A VCAM-like adhesion molecule on murine bone marrow stromal cells mediates binding of lymphocyte precursors in culture
24. Regulation of human B-cell precursor adhesion to bone marrow stromal cells by cytokines that exert opposing effects on the expression of vascular cell adhesion molecule-1 (VCAM-1)
25. Impaired ability of bone marrow stromal cells to support B-lymphopoiesis with age
26. Vascular cell adhesion molecule-1 and the integrin VLA-4 mediate adhesion of human B cell precursors to cultured bone marrow adherent cells
27. Maturation-dependent adhesion of human B cell precursors to the bone marrow microenvironment
28. Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis
29. Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-κB subunits in endothelial and epithelial cells
30. Cell type-specific transactivation of the VCAM-1 promoter through an NF-κB enhancer motif
31. Endothelial interferon regulatory factor 1 cooperates with NF-κB as a transcriptional activator of vascular cell adhesion molecule 1
32. Independent modes of transcriptional activation by the p50 and p65 subunits of NF-κB
33. Sp1 is a component of the cytokine-inducible enhancer in the promoter of vascular cell adhesion molecule-1
34. In vivo control of NF-κB activation by IκBα
35. NF-κB controls expression of inhibitor IκBα: Evidence for an inducible autoregulatory pathway
36. Nuclear factor kappa B: Important transcription factor and therapeutic target
37. TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
38. + T lymphocytes
39. p38 mitogen activated protein kinase regulates endothelial VCAM-1 expression at the post-transcriptional level
40. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
41. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
42. Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is a potent inhibitor of nuclear transcription factor-κB activation by diverse agents
43. Functional analysis of the human vascular cell adhesion molecule 1 promoter
44. Induction of Sp1 in differentiating human embryonal carcinoma cells triggers transcription of the fibronectin gene
45. The fibronectin gene as a model for splicing and transcription studies
46. Transcriptional regulation of endothelial cell adhesion molecules: NF-κB and cytokine-inducible enhancers
47. Role of activating protein-1 in the regulation of the vascular cell adhesion molecule-1 gene expression by tumor necrosis factor-α
48. Interspecies differences in in vitro etoposide plasma protein binding
49. In vitro metabolism of etoposide (VP-16-213) by liver microsomes and irreversible binding of reactive intermediates to microsomal proteins
50. Three NF-κB sites in the IκB-α promoter are required for induction of gene expression by TNFα
51. The regulation of GM-CSF is dependent on a complex interplay of multiple nuclear proteins