Time course of increasing numbers of mutations in the granulocyte colony-stimulating factor receptor gene in a patient with congenital neutropenia who developed leukemia

Blood

Volumn 97, Issue 6, 2001, Pages 1882-1884

  Tschan, Christoph A ^a   Pilz, Christina ^a   Zeidler, Cornelia ^a   Welte, Karl ^a   Germeshausen, Manuela ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; MESSENGER RNA;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; DISEASE ASSOCIATION; DNA SEQUENCE; FEMALE; GENE MUTATION; GENETIC STABILITY; HUMAN; MONONUCLEAR CELL; NEUTROPENIA; NEUTROPHIL; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

EID: 0035869624     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V97.6.1882     Document Type: Article

References (7)

1. Severe chronic neutropenia: Pathophysiology and therapy
2. Risk-adapted therapy and randomization in children with AML: Preliminary results of study AML-BFM 93
3. G-CSF receptor mutations in patients with congenital neutropenia: Frequency and implications in leukemic development
4. Myelodysplasia syndrome and acute myeloid leukemia in patients with congenital neutropenia receiving G-CSF therapy
5. Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia
6. Clinical relevance of point mutations in the cytoplasmic domain of the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia
7. Three different mRNAs encoding human granulocyte colony-stimulating factor receptor