The cyclin-dependent kinase inhibitor (CDKI) flavopiridol disrupts phorbol 12-myristate 13-acetate-induced differentiation and CDKI expression while enhancing apoptosis in human myeloid leukemia cells

Cancer Research

Volumn 61, Issue 6, 2001, Pages 2583-2591

  Cartee, Leanne ^a   Wang, Zhiliang ^a   Decker, Roy H ^a   Chellappan, Srikumar P ^b   Fusaro, Gina ^b   Hirsch, Karen G ^a   Sankala, Heidi M ^a   Dent, Paul ^a   Grant, Steven ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b Columbia University College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CASPASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYTOCHROME C; FLAVOPIRIDOL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN BCL 2; PROTEIN P21; RETINOBLASTOMA PROTEIN;

APOPTOSIS; ARTICLE; CELL CLONE; CELL DIFFERENTIATION; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME ACTIVATION; ENZYME RELEASE; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOLECULAR INTERACTION; MORPHOLOGY; MYELOID LEUKEMIA; PRIORITY JOURNAL;

APOPTOSIS; CARRIER PROTEINS; CASPASES; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; E2F TRANSCRIPTION FACTORS; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVONOIDS; HL-60 CELLS; HUMANS; MEMBRANE POTENTIALS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PIPERIDINES; PROTEIN BINDING; RETINOBLASTOMA PROTEIN; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; U937 CELLS;

EID: 0035866782     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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