A 3′-transcribed region of the HLA-A2 gene mediates posttranscriptional stimulation by IFN-γ

Journal of Immunology

Volumn 166, Issue 6, 2001, Pages 3966-3974

  Snyder, S R ^a   Waring, J F ^a   Zu Zhu, S ^a   Kaplan, S ^a   Schultz, J ^a   Ginder, G D ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HLA A2 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MESSENGER RNA; HLA A ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; GENE CONSTRUCT; GENE CONTROL; GENE INDUCTION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; RNA STABILITY; TUMOR CELL LINE; 3' UNTRANSLATED REGION; ALTERNATIVE RNA SPLICING; BIOSYNTHESIS; CELL STRAIN K 562; CELL STRAIN U937; GENE; GENE EXPRESSION REGULATION; GENETICS; HALF LIFE TIME; HELA CELL; IMMUNOLOGY; METABOLISM; NUCLEOTIDE SEQUENCE; RNA PROCESSING;

3' UNTRANSLATED REGIONS; ALTERNATIVE SPLICING; BASE SEQUENCE; GENE EXPRESSION REGULATION; GENES, MHC CLASS I; HALF-LIFE; HELA CELLS; HLA-A ANTIGENS; HLA-A2 ANTIGEN; HUMANS; INTERFERON TYPE II; JURKAT CELLS; K562 CELLS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSFECTION; U937 CELLS;

EID: 0035866561     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.6.3966     Document Type: Article

References (58)

1. Interferon increases HLA synthesis in melanoma cells: Interferon-resistant and -sensitive cell lines
2. Differential regulation of HLA-DR mRNAs and cell surface antigens by interferon
3. Control of haemoglobin switching by a developmental clock?
4. Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells
5. 2 microglobulin and immunoselection in the pathway to malignancy
6. Oncogenes and signal transduction
7. Diversity of cytoplasmic functions for the 3′ untranslated region of eukaryotic transcripts
8. Genes of the major histocompatibility complex of the mouse
9. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
10. MHC-restricted cytotoxic T cells: Studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness
11. Interrelations between the maturation of 100 kDa nucleolar protein and pre rRNA synthesis in cells
12. γ interferon and 5-azacytidine cause transcriptional elevation of class I major histocompatibility complex gene expression in K562 leukemia cells in the absence of differentiation
13. Detailed analysis of the mouse H-2kb promoter: Enhancer-like sequences and their role in the regulation of class I gene expression
14. Molecular genetics of chronic myelogenous leukemia
15. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signalling proteins
16. Critical role of a common transcription factor, IRF-1, in the regulation of IFN-β and IFN-inducible genes
17. Regulation of murine class I genes by interferons is controlled by regions located both 5′ and 3′ to the transcriptional initiation site
18. Regulation of gene expression by interferons: Control of H-2 promoter responses
19. Regulated expression of multiple chicken erythroid membrane skeletal protein 4.1 variants is governed by differential RNA processing and translational control
20. Transcripts of human HLA gene fragments lacking the 5′-terminal region in transfected mouse cells
21. Identification of cis sequences controlling efficient position-independent tissue-specific expression of human major histocompatibility complex class I genes in transgenic mice
22. The human leukocyte antigen A2 interferon-stimulated response element consensus sequence binds a nuclear factor required for constitutive expression
23. Differential regulation of HLA-A3 and HLA-B7 MHC class I genes by IFN is due to two nucleotide differences in their IFN response sequences
24. Transcriptional activation of HLA-Dra by interferon γ requires a trans-acting protein
25. Increased rate of degradation of c-myc mRNA in interferon-treated Daudi cells
26. HLA class I nucleotide sequences
27. Human triosephosphate isomerase deficiency resulting from mutation of Phe-240
28. "Nonrandom" DNA sequence analysis in bacteriophage M13 by the dideoxy chain-termination method
29. DNA sequencing with chain-terminating inhibitors
30. Only the HLA class I gene minimal promoter elements are required for transactivation by human cytomegalovirus immediately early genes
31. Stimulation of MHC class I transcription by interferon-γ involves a non-A, non-C kinase in addition to protein kinase C
32. Negative and positive regulation of HLA class I gene transcription in K562 leukemia cells
33. Isolation and partial nucleotide sequence of a cDNA clone for human histocompatibility antigen HLA-B by use of an oligonucleotide primer
34. Cloning and complete sequence of an HLA-A2 gene: Analysis of two HLA-A alleles at the nucleotide level
35. Interferons increase transcription of a major histocompatibility class I gene via a 5′ interferon consensus sequence
36. Cell-type specificity of interferon-γ-mediated HLA class I gene transcription in human hematopoietic tumor cells
37. HLA class I sequence-based typing
38. Why HeLa cells do not produce interferon
39. Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells
40. The activation of major histocompatibility complex class I genes by interferon regulatory factor-1 (IRF-1)
41. Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both β interferon- and interferfon-stimulated genes but is not a primary transcriptional activator of either
42. HLA class I noncoding nucleotide sequences, 1992
43. The HLA-AW24 gene: Sequence, surroundings and comparison with the HLA-A2 and HLA-A3 genes
44. Complete nucleotide sequence of a functional class I HLA gene, HLA-A3: Implications for the evolution of HLA genes
45. Nucleotide sequence of the HLA-A26 class I gene: Identification of specific residues and molecular mapping of public HLA class I epitopes
46. IFN-γ up-regulates expression of the complement components C3 and C4 by stabilization of mRNA
47. Interferon-γ- and phorbol myristate acetate-responsive elements involved in intercellular adhesion molecule-1 mRNA stabilization
48. Bryostatin-1 and IFN-γ synergize for the expression of the inducible nitric oxide synthase gene and for nitric oxide production in murine macrophages
49. Enhanced B7-2 gene expression by interferon-γ in human monocytic cells is controlled through transcriptional and posttranscriptional mechanisms
50. Interferon-γ improves splicing efficiency of CYBB gene transcripts in an interferon-responsive variant of chronic granulomatous disease due to a splice site consensus region mutation
51. Transcriptional regulation of the interferon-γ-inducible triptophanyl-tRNA synthetase includes alternative splicing
52. A novel type of splicing enhancer regulating adenoviros pre-mRNA splicing
53. Exonic splicing enhancers: Mechanism of action, diversity and role in human genetic diseases
54. Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins
55. Nuclear RNA export pathways
56. Splicing is required for rapid and efficient mRNA export in metazoans
57. Differential regulation of HLA class I genes by interferon
58. Interferon-γ induction of the human leukocyte antigen-E gene is mediated through binding of a complex containing STAT1a to a distinct interferon-γ-responsive element