Detection and clinical associations of antiprothrombin antibodies

American Journal of Medicine

Volumn 110, Issue 3, 2001, Pages 229-230

  Donohoe, Siobhán ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; BETA2 GLYCOPROTEIN 1; LUPUS ANTICOAGULANT; PHOSPHOLIPID ANTIBODY; PHOSPHOLIPID BINDING PROTEIN; PROTHROMBIN; PROTHROMBIN ANTIBODY; UNCLASSIFIED DRUG;

ANTIBODY AFFINITY; ANTIBODY DETECTION; ANTICOAGULATION; ANTIGEN BINDING; ANTIPHOSPHOLIPID SYNDROME; BLEEDING TENDENCY; CLINICAL FEATURE; CLINICAL TRIAL; CROSSED IMMUNOELECTROPHORESIS; DIAGNOSTIC ACCURACY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HYPOPROTHROMBINEMIA; IMMUNOASSAY; IMMUNODIFFUSION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; SHORT SURVEY; TECHNIQUE; THROMBOSIS;

EID: 0035865818     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9343(00)00738-5     Document Type: Editorial

References (14)

1. Syndrome of the black Swan
2. Prothrombin as co-factor of the circulating anticoagulant in systemic lupus erythematosus?
3. Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor
4. Acquired hypoprothrombinemia due to non-neutralizing antibodies to prothrombin: Mechanism and management
5. Anti-prothrombin antibodies and the lupus anticoagulant
6. Abnormal prothrombin crossed-immunoelectrophoresis in patients with lupus inhibitors
7. Lupus anticoagulant IgG's (lupus anticoagulant) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin
8. Lupus anticoagulants form immune complexes with prothrombin and phospholipid that can augment thrombin production in flow
9. An IgG antiprothrombin antibody enhances prothrombin binding to damaged endothelial cells and shortens plasma coagulation times
10. Anti-prothrombin autoantibodies in severe pre-eclampsia and abortion
11. Mechanism and effects of the binding of lupus anticoagulant IgG and prothrombin to surface phospholipid
12. Prothrombin fragment F1-2: The epitope for antiphospholipid expression
13. Relationship between clinical features and binding domains of anti-prothrombin autoantibodies in patients with systemic lupus erythematosus and antiphospholipid syndrome