Phase I bioequivalency study of MitoExtra and mitomycin C in patients with solid tumors

Cancer

Volumn 91, Issue 4, 2001, Pages 815-821

  Kozuch, Peter ^a   Hoff, Paulo M ^a,d   Hess, Kenneth ^a   Adams, Jennifer ^a   Newman, Robert A ^a   Lee, Francis ^b   Pazdur, Richard ^c  

^a UNIVERSITY OF TEXAS   (United States)

^b Supergen   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^d Box 78 ^*  (United States)

Author keywords

Cancer; MitoExtra; Mitomycin C; Pharmacokinetics; Phase I; Solid tumors

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; DRUG CARRIER; MITOEXTRA; MITOMYCIN; MITOMYCIN C;

ABDOMINAL PAIN; ADULT; AGED; ALOPECIA; ANOREXIA; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; BLOOD TOXICITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONJUNCTIVITIS; CROSSOVER PROCEDURE; DIARRHEA; DRUG CLEARANCE; DRUG DISPOSITION; DRUG FORMULATION; DRUG HALF LIFE; DRUG RELEASE; FATIGUE; FEMALE; HUMAN; MALE; NAUSEA AND VOMITING; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; SERUM; SOLID TUMOR; STOMATITIS; URINE;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; BETA-CYCLODEXTRINS; CROSS-OVER STUDIES; CYCLODEXTRINS; FEMALE; HUMANS; MALE; MIDDLE AGED; MITOMYCIN; NEOPLASMS; THERAPEUTIC EQUIVALENCY;

EID: 0035865011     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0142(20010215)91:4<815::AID-CNCR1069>3.0.CO;2-J     Document Type: Article

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