Coexistence of thrombophilic gene polymorphisms among 559 unrelated consecutive patients with a history of thrombosis [1]

Thrombosis Research

Volumn 101, Issue 4, 2001, Pages 317-319

  Madonna, Pasquale ^a,c   Piemontino, Umberto ^a   DeStefano, Valentino ^a   Albisinni, Rosina ^a   Cerbone, Anna Maria ^a   Di Minno, Giovanni ^b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF PALERMO   (Italy)

^c Clinica Medica   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); BLOOD CLOTTING FACTOR 5 LEIDEN; HOMOCYSTEINE; PROTHROMBIN;

ADULT; ARTERY THROMBOSIS; DEEP VEIN THROMBOSIS; ENZYME ACTIVITY; FEMALE; GENETIC POLYMORPHISM; GENETIC RISK; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; LETTER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; THROMBOPHILIA; THROMBOSIS;

ADULT; CASE-CONTROL STUDIES; FACTOR V; FEMALE; HUMANS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; POLYMORPHISM, GENETIC; PROTHROMBIN; RISK FACTORS; THROMBOPHILIA; THROMBOSIS; VENOUS THROMBOSIS;

EID: 0035864774     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(00)00416-3     Document Type: Letter

References (14)

1. Risk factors for venous thrombotic disease
2. Mutation in blood coagulation factor V associated with resistance to activated protein C
3. Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke and venous thrombosis in apparently healthy men
4. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis
5. G20210A mutation in prothrombin gene and risk of myocardial infarction, stroke and venous thrombosis in a large cohort of US men
6. Hyperhomocysteinemia: An independent risk factor for vascular disease
7. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
8. The risk of recurrent deep venous thrombosis among heterozygous carriers of both factor V Leiden and G20210A prothrombin mutation
9. Coexistence of factor V Leiden and factor II A20210 mutation and recurrent venous thromboembolism
10. Single and combined prothrombotic factors in patients with idiopathic venous thromboembolism. Prevalence and risk assessment
11. 506)
12. Effect of methylenetetrahydrofolate reductase 677 C → T, 1298 A → C, and 1317 T → C on Factor V 1691 mutation in Turkish deep vein thrombosis patients
13. No evidence for an increased risk of venous thrombosis in patients with Factor V Leiden by the homozygous 677 C to T mutation in the methylenetetrahydrofolate reductase gene
14. The G20210A mutation of the prothrombin gene in patients with previous first episodes of deep vein thrombosis: Prevalence and association with factor V G1691A, methylenetetrahydrofolate reductase C677T and plasma prothrombin levels