Analysis of adaptive response to bleomycin and mitomycin C

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 513, Issue 1-2, 2001, Pages 75-81

  Schlade Bartusiak, Kamila ^a   Stembalska Kozlowska, Agnieszka ^a   Bernady, Monika ^a   Kudyba, Marta ^a   Sasiadek, Maria ^a  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

Adaptive response; Bleomycin; DNA damage repair; Mitomycin C

Indexed keywords

ALKYLATING AGENT; BLEOMYCIN; CHEMICAL MUTAGEN; DOUBLE STRANDED DNA; MITOMYCIN C; SINGLE STRANDED DNA;

ADULT; ARTICLE; CHROMOSOME ABERRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOGENETICS; DNA CROSS LINKING; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; GENETIC STABILITY; HUMAN; INDIVIDUALITY; LYMPHOCYTE; METHODOLOGY; MUTAGEN TESTING; PRIORITY JOURNAL; SISTER CHROMATID EXCHANGE;

ADAPTATION, PHYSIOLOGICAL; ADULT; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; CHROMOSOME ABERRATIONS; DNA REPAIR; FEMALE; HUMANS; MALE; MITOMYCIN; SISTER CHROMATID EXCHANGE;

EID: 0035863854     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1383-5718(01)00288-1     Document Type: Article

References (23)

1. Recurrent chromosome aberrations in cancer
2. DNA-damage and repair: Consequences on dose-responses
3. Markers of DNA-repair and susceptibility to cancer in humans: An epidemiologic review
4. Sensitivity to genotoxic effects of bleomycin in humans: Possible relationship to environmental carcinogenesis
5. Chromosome instability in head and neck cancer patients
6. Increased mutagen sensitivity in head and neck squamous-cell carcinoma patients, particularly those with multiple primary tumours
7. Association between bleomycin genotoxicity and non-constitutional risk factors for head and neck cancer
8. Latent chromosomal instability in cancer patients
9. Protective effects of vitamin E against bleomycin-induced genotoxicity in head and neck cancer patients in vitro
10. Bleomycin-induced chromosome damage in lymphocytes indicates inefficient DNA-repair capacity in breast cancer families
11. Value of pedigree/clinical data, immunohistochemistry and microsatellite instability analyses in reducing the cost of determining hMLH1 and hMSH2 gene mutations in patients with colorectal cancer
12. Increased levels of mutagen-induced chromosome breakage in Down syndrome children with malignancy
13. 1 phase human lymphocytes
14. Mechanisms of the adaptive response in irradiated mammalian cells
15. Radio adaptation for gene mutation and the possible molecular mechanisms of the adaptive response
16. Resistance and cross-resistance to chromosome damage in human lymphocytes adapted to bleomycin
17. Adaptation of human lymphocytes to radiation or chemical mutagens: Differences in cytogenetic repair
18. Adaptive and synergistic effects of a low-dose ENU pre-treatment on the frequency of chromosomal aberrations induced by a challenge dose of ENU in human peripheral blood lymphocytes in vitro
19. Correlation between the adaptive response and individual sensitivity to monoepoxybutene in in vitro experiments on human lymphocytes
20. Mutagenic damage to mammalian cells by therapeutic alkylating agents
21. Smoking and sister chromatid exchange
22. Is Fanconi anaemia caused by a defect in the processing of DNA-damage?
23. Repair of DNA lesions: Mechanisms and relative repair efficiencies