Identification of domains and amino acids involved in GluR7 ion channel function

Journal of Neuroscience

Volumn 21, Issue 2, 2001, Pages 401-411

  Strutz, Nathalie ^a   Villmann, Carmen ^b   Thalhammer, Agnes ^a   Kizelsztein, Pablo ^c   Eisenstein, Miriam ^c   Teichberg, Vivian I ^c   Hollmann, Michael ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Chimeras; Coexpression; GluR6; GluR7; Glutamate receptors; Ion channel function; Kainate receptors; Point mutations

Indexed keywords

AMINO ACID; CONCANAVALIN A; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR 6; GLUTAMATE RECEPTOR 7; ION CHANNEL; KAINIC ACID; KAINIC ACID RECEPTOR; LECTIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CHIMERA; CONTROLLED STUDY; DESENSITIZATION; HUMAN; HUMAN CELL; MEMBRANE CURRENT; NONHUMAN; OOCYTE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; XENOPUS;

EID: 0035862953     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-02-00401.2001     Document Type: Article

References (20)

1. Structure of a glutamate-receptor ligand-binding core in complex with kainate
2. Cloning of a putative glutamate receptor: A low affinity kainate binding subunit
3. Spatial distribution of kainate receptor subunit messenger RNA in the mouse basal ganglia and ventral mesencephalon
4. Heteromeric kainate receptors formed by the coassembly of GluR5, GluR6, and GluR7
5. The glutamate receptor ion channels
6. N-glycosylation is not a prerequisite for glutamate receptor function but is essential for lectin modulation
7. Structure of ionotropic glutamate receptors
8. Cloned glutamate receptors
9. N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1
10. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
11. High-affinity kainate and domoate receptors in rat brain
12. The NMDA receptor
13. Molecular characterization of the human EAA5 (GluR7) receptor: A high-affinity kainate receptor with novel potential RNA editing sites
14. Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A
15. Rat GluR7 and a carboxy-terminal splice variant, GluR7b, are functional kainate receptor subunits with a low sensitivity to glutamate
16. Identification of amino acid residues that control functional behavior in GluR5 and GluR6 kainate receptors
17. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
18. Kainate binding proteins possess functional ion channel domains
19. Investigation by ion channel domain transplantation of rat glutamate receptor subunits, orphan receptors and a putative NMDA receptor subunit
20. Biochemical and assembly properties of GluR6 and KA2, 2 members of the kainate receptor family, determined with subunit specific antibodies