Haem regulation of the mitochondrial import of the Kluyveromyces lactis 5-aminolaevulinate synthase: An organelle approach

Yeast

Volumn 18, Issue 1, 2001, Pages 41-48

  Gonzalez Dominguez M ^a   Freire Picos, M A ^a   Cerdan M E ^a  

^a UNIVERSITY OF A CORUÑA   (Spain)

Author keywords

5 aminolaevulinate acid synthase; Haem biosynthesis; HEM; HRM; Kluyveromyces lactis; Mitochondria

Indexed keywords

5 AMINOLEVULINATE SYNTHASE; HEME; RECOMBINANT DNA;

ARTICLE; BIOSYNTHESIS; CATALYSIS; CELL ORGANELLE; ENZYME ACTIVITY; ENZYME LOCALIZATION; KLUYVEROMYCES; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; YEAST;

5-AMINOLEVULINATE SYNTHETASE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BASE SEQUENCE; ENZYME PRECURSORS; FEEDBACK; HEME; HEMIN; KLUYVEROMYCES; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS;

EUKARYOTA; KLUYVEROMYCES LACTIS;

EID: 0035862740     PISSN: 0749503X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0061(200101)18:1<41::AID-YEA654>3.0.CO;2-E     Document Type: Article

References (21)

1. Regulation of heme biosynthesis in higher animals
2. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
3. Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha; (eIF-2 α) kinase of rabbit reticulocytes: Homology to yeast GCN2 protein kinase and human double-stranded RNA-dependent eIF-2 α kinase
4. Phylogenetic analysis of the 5-aminolaevulinate synthase gene
5. Isolation and characterisation of the K1HEM1 gene in Kluyveromyces lactis
6. Isolation of yeast mitochondria and study of mitochondrial protein translation
7. Constitutive expression of the yeast HEM1 gene is actually a composite of activation and repression
8. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
9. Regulation by heme of mitochondrial protein transport through a conserved amino acid motif
10. Control of 5-aminolaevulinate synthase in animals
11. Heme oxygenase-2 is a haemoprotein and binds heme through heme regulatory motifs that are not involved in heme catalysis
12. Schizosaccharomyces pombe mitochondria: Morphological, respiratory and protein import characteristics
13. Protein import into mitochondria
14. An efficient mRNA-dependent translation system from reticulocyte lysates
15. Functional dissection and sequence of yeast HAP1 activator
16. Cell biology of heme
17. Heme binding to a conserved Cys-Pro-Val motif is crucial for the catalytic function of mitochondrial heme lyases
18. The nucleotide sequence of the HEM1 gene and evidence for a precursor form of the mitochondrial 5-aminolaevulinate synthase in Saccharomyces cerevisiae
19. The presequence of yeast 5-aminolaevulinate synthase is not required for targeting to mitochondria
20. Heme binds to a short sequence that serves a regulatory function in diverse proteins