Inhibition of DNA Cross-linking by Mitomycin C by Peroxidase-mediated Oxidation of Mitomycin C Hydroquinone

Journal of Biological Chemistry

Volumn 276, Issue 37, 2001, Pages 34445-34452

  Penketh, Philip G ^a   Hodnick, William F ^a,d   Belcourt, Michael F ^a,d   Shyam, Krishnamurthy ^a   Sherman, David H ^b,c   Sartorelli, Alan C ^a  

^a YALE CANCER CENTER   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c University of Minnesota   (United States)

^d Vion Pharmaceuticals Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CROSSLINKING; DNA; ENZYMES; OXIDATION; SENSITIVITY ANALYSIS;

ANTICANCER ACTIVITY;

BIOCHEMISTRY;

DNA; EDETIC ACID; HORSERADISH PEROXIDASE; HYDROGEN PEROXIDE; LACTOPEROXIDASE; MITOMYCIN C; MITOMYCIN C DERIVATIVE; MITOMYCIN C HYDROQUINONE; MYELOPEROXIDASE; SODIUM BOROHYDRIDE; TROMETAMOL; UNCLASSIFIED DRUG; BORANE DERIVATIVE; HYDROQUINONE; HYDROQUINONE DERIVATIVE; MITOMYCIN; PEROXIDASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BACTERIOPHAGE T7; DNA CROSS LINKING; DNA REPAIR; DRUG INACTIVATION; DRUG SENSITIVITY; PRIORITY JOURNAL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

ARMORACIA RUSTICANA;

BOROHYDRIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; HYDROQUINONES; MITOMYCIN; OXIDATION-REDUCTION; PEROXIDASES;

EID: 0035860763     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104263200     Document Type: Article

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