Amyloid precursor protein associates independently and collaboratively with PTB and PDZ domains of mint on vesicles and at cell membrane

Neuroscience

Volumn 104, Issue 3, 2001, Pages 653-665

  Okamoto, M ^b   Nakajima, Y ^a   Matsuyama, T ^a   Sugita, M ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Mint; PDZ domain; PTB domain; Vesicle trafficking

Indexed keywords

ADAPTOR PROTEIN; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GREEN FLUORESCENT PROTEIN; ION CHANNEL; MINT 1 PROTEIN; MINT 2 PROTEIN; MINT 3 PROTEIN; PHOSPHOTYROSINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; ENDOCYTOSIS; EPENDYMA CELL; EPITHELIUM CELL; GLIA CELL; GOLGI COMPLEX; HUMAN; HUMAN CELL; IN SITU HYBRIDIZATION; MACROMOLECULE; MALE; MOUSE; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SITE DIRECTED MUTAGENESIS; SYNAPSE VESICLE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; CELL MEMBRANE; CELLS, CULTURED; GENE EXPRESSION REGULATION; MALE; MICE; MICE, INBRED C57BL; NEURONS; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTEINS; RNA, MESSENGER; TRANSPORT VESICLES;

EID: 0035859209     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(01)00124-5     Document Type: Article

References (35)

1. The phosphotyrosine interaction domain of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein
2. Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting
3. Molecular analysis of the X11-mLin-2/CASK complex in brain
4. A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain
5. Crystal structure of a PDZ domain
6. Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer β/A4 amyloid precursor protein
7. PDZ proteins organize synaptic signaling pathways
8. Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition
9. Crystal structure of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ
10. A role for a PDZ protein in the early secretory pathway for the targeting of pro TGF-α to the cell surface
11. + channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein
12. Clustering membrane proteins: Its all coming together with the PSD-95/SAP90 family
13. The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells
14. Effects of recombinant superoxide dismutase on manganese superoxide dismutase gene expression in gerbil hippocampus after ischemia
15. Association of neuronal calcium channels with modular adapter proteins
16. The intracellular cytoplasmic domain of the Alzheimers disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system
17. Mint2/X11-like colocalizes with the Alzheimers disease amyloid precursor protein and is associated with neuritic plaques in Alzheimers disease
18. Mints, munc18-interacting protein in synaptic vesicle exocytosis
19. Mint3: A ubiquitous mint isoform that does not bind to munc18-1 or -2
20. Ultrastructural localization of mint1 at synapses in mouse hippocampus
21. Ligand-dependent G protein coupling function of amyloid transmembrane precursor
22. PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells
23. LIN-10 is a shared component of the polarized protein localization pathways in neurons and epithelia
24. X11 interaction with β-amyloid precursor protein modulates its cellular stabilization and reduces amyloid β-protein secretion
25. Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons
26. The cell biology of beta-amyloid precursor protein and presenilin in Alzheimers disease
27. Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport
28. PDZs and receptor/channel clustering: Rounding up the latest suspects
29. The β-amyloid domain is essential for axonal sorting of amyloid precursor protein
30. Interaction of a neuron-specific protein containing PDZ domains with Alzheimers amyloid precursor protein
31. PDZ domain-dependent suppression of NF-κB/p65-induced Aβ42 production by a neuron-specific X11-like protein
32. Basolateral localization of the Caenorhabditis elegans epidermal growth factor receptor in epithelial cells by the PDZ protein LIN-10
33. Trafficking of cell surface β-amyloid precursor protein: Retrograde and transcytotic transport in cultured neurons
34. Sequence-specific recognition of the internalization motif of the Alzheimers amyloid precursor protein by the X11 PTB domain
35. Structure and ligand recognition of the phosphotyrosine binding domain of Shc