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Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1535, Issue 2, 2001, Pages 164-173

The measured level of prion infectivity varies in a predictable way according to the aggregation state of the infectious agent

(2) Masel, Joanna a,c Jansen, Vincent A A b

a UNIVERSITY OF OXFORD (United Kingdom)

b UNIVERSITY OF LONDON (United Kingdom)

c STANFORD UNIVERSITY (United States)

Author keywords

Amyloid; Incubation time assay; Mathematical model; One hit model; Prion disease; Protein aggregation

Indexed keywords

LIPOSOME; POLYMER; PRION PROTEIN;

ARTICLE; BRAIN SPONGIOSIS; CONTROLLED STUDY; INCUBATION TIME; INFECTION; INTERMETHOD COMPARISON; KINETICS; LD 50; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MOLECULAR SIZE; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; PROTEIN AGGREGATION; TITRIMETRY;

ANIMALS; HUMANS; LETHAL DOSE 50; MODELS, BIOLOGICAL; MOLECULAR WEIGHT; POLYMERS; PRION DISEASES; PRPSC PROTEINS;

EID: 0035857483 PISSN: 09254439 EISSN: None Source Type: Journal
DOI: 10.1016/S0925-4439(00)00095-8 Document Type: Article

Times cited : (26)

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