Promoter-specific activation defects by a novel yeast TBP mutant compromised for TFIIB interaction

Current Biology

Volumn 11, Issue 22, 2001, Pages 1794-1798

  Virbasius, Ching Man A ^a   Holstege, Frank C ^b   Young, Richard A ^b   Green, Michael R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0035856501     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00566-8     Document Type: Article

References (26)

1. Mechanism of action of an acidic transcriptional activator in vitro
2. Activation of RNA polymerase II transcription by the specific DNA-binding protein LSF. Increased rate of binding of the basal promoter factor TFIIB
3. Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II)
4. Interaction between a transcriptional activator and transcription factor IIb in vivo
5. Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation
6. Activator-induced conformational change in general transcription factor TFIIB
7. A role for activator-mediated TFIIB recruitment in diverse aspects of transcriptional regulation
8. Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation
9. Human general transcription factor TFIIB: Conformational variability and interaction with VP16 activation domain
10. An activation-specific role for transcription factor TFIIB in vivo
11. The conformation of the transcription factor TFIIB modulates the response to transcriptional activators in vivo
12. Crystal structure of a TFIIB-TBP-TATA-element ternary complex
13. Radical mutations reveal TATA-box binding protein surfaces required for activated transcription in vivo
14. Protein-protein interactions in eukaryotic transcription initiation: Structure of the preinitiation complex
15. Mutations on the DNA-binding surface of TATA-binding protein can specifically impair the response to acidic activators in vivo
16. Yeast and human TFIID with altered DNA-binding specificity for TATA elements
17. A severely defective TATA-binding protein-TFIIB interaction does not preclude transcriptional activation in vivo
18. The TBP-TFIIA interaction in the response to acidic activators in vivo
19. Dissecting the regulatory circuitry of a eukaryotic genome
20. Enhancement of TBP binding by activators and general transcription factors
21. II 145 functions as a core promoter selectivity factor, not a general coactivator
22. II present in TFIID and SAGA
23. The ability to associate with activation domains in vitro is not required for the TATA box-binding protein to support activated transcription in vivo
24. TBP mutants defective in activated transcription in vivo
25. Association of transcription factor IIA with TATA binding protein is required for transcriptional activation of a subset of promoters and cell cycle progression in Saccharomyces cerevisiae
26. Transcriptional activation in yeast cells lacking transcription factor IIA