The inhibition of gluconeogenesis by chloroquine contributes to its hypoglycaemic action

European Journal of Pharmacology

Volumn 428, Issue 3, 2001, Pages 381-388

  Jarzyna, Robert ^a   Kiersztan, Anna ^a   Lisowa, Olesia ^a   Bryla, Jadwiga ^a  

^a UNIVERSITY OF WARSAW   (Poland)

Author keywords

Chloroquine; Gluconeogenesis; Hepatocyte; Hypoglycaemia; Renal tubule

Indexed keywords

2 OXOGLUTARIC ACID; AMINO ACID; AMMONIUM CHLORIDE; CHLOROQUINE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLUTAMATE DEHYDROGENASE; GLUTAMIC ACID; GLUTAMINE; GLYCEROL; OCTANOIC ACID; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); UREA;

ALLOXAN DIABETES MELLITUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL LEVEL; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; GLUCONEOGENESIS; INHIBITION KINETICS; KIDNEY; KIDNEY CORTEX; KIDNEY TUBULE; LIVER; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; UREA CYCLE;

ALLOXAN; ANIMALS; CHLOROQUINE; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCONEOGENESIS; GLUCOSE; GLUCOSE-6-PHOSPHATASE; GLUCOSEPHOSPHATE DEHYDROGENASE; HEPATOCYTES; HYPOGLYCEMIC AGENTS; KIDNEY TUBULES; MALE; OXYGEN CONSUMPTION; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PYRUVATE CARBOXYLASE; RABBITS; SUBSTRATE SPECIFICITY;

EID: 0035850674     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)01221-3     Document Type: Article

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