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Volumn 333, Issue 3, 2001, Pages 203-231
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Synthesis of lipid A type pyran carboxylic acids with ether chains and their biological activities
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Author keywords
Endotoxin; Lipid A; LPS agonist; LPS antagonist; TNF production inhibitor
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Indexed keywords
BIOSYNTHESIS;
CELLS;
ETHERS;
LIPIDS;
BIOACTIVITIES;
CARBOXYLIC ACIDS;
2,6 ANHYDRO 7 O [2 ACETAMIDO 2 DEOXY 3 O [3 (DODECYLOXY)TETRADECYL] 4 O PHOSPHONO BETA DEXTRO GLUCOPYRANOSYL] 3 [3 (HYDROXY)TETRADECANAMIDO] 4 O [3 (HYDROXY)TETRADECYL] 3 DEOXY DEXTRO GLYCERO DEXTRO IDO HEPTONIC ACID;
2,6 ANHYDRO 7 O [2 ACETAMIDO 2 DEOXY 3 O [3 (DODECYLOXY)TETRADECYL] 6 O METHYL 4 O PHOSPHONO BETA DEXTRO GLUCOPYRANOSYL] 3 [3 (HYDROXY)TETRADECANAMIDO] 4 O [3 (HYDROXY)TETRADECYL] 3 DEOXY DEXTRO GLYCERO DEXTRO IDO HEPTONIC ACID;
2,6 ANHYDRO 7 O [2 ACETAMIDO 2 DEOXY 4 O PHOSPHONO 3 O [3 (TETRADECANOYLOXY)TETRADECYL] BETA DEXTRO GLUCOPYRANOSYL] 3 DEOXY 3 [3 (HYDROXY)TETRADECANAMIDO] 4 O [3 (HYDROXY)TETRADECYL] DEXTRO GLYCERO DEXTRO IDO HEPTONIC ACID;
2,6 ANHYDRO 7 O [2 ACETAMIDO 2 DEOXY 6 O METHYL 4 O PHOSPHONO 3 O [3 (TETRADECANOYLOXY)TETRADECYL] BETA DEXTRO GLUCOPYRANOSYL] 3 DEOXY 3 [3 (HYDROXY)TETRADECANAMIDO] 4 O [3 (HYDROXY)TETRADECYL] DEXTRO GLYCERO DEXTRO IDO HEPTONIC ACID;
2,6 ANHYDRO 7 O [2 ACETAMIDO 2,6 DIDEOXY 3 O [3 (DODECYLOXY)TETRADECYL] 6 FLUORO 4 O PHOSPHONO BETA DEXTRO GLUCOPYRANOSYL] 3 [3 (HYDROXY)TETRADECANAMIDO] 4 O [3 (HYDROXY)TETRADECYL] 3 DEOXY DEXTRO GLYCERO DEXTRO IDO HEPTONIC ACID;
2,6 ANHYDRO 7 O [2 ACETAMIDO 2,6 DIDEOXY 6 FLUORO 4 O PHOSPHONO 3 O [3 (TETRADECANOYLOXY)TETRADECYL] BETA DEXTRO GLUCOPYRANOSYL] 3 DEOXY 3 [3 (HYDROXY)TETRADECANAMIDO] 4 O [3 (HYDROXY)TETRADECYL] DEXTRO GLYCERO DEXTRO IDO HEPTONIC ACID;
2,6 ANHYDRO 7 O [2 DEOXY 2 [3 (DODECANOYLOXY)TETRADECANAMIDO] 4 O PHOSPHONO 3 O [3 (TETRADECANOYLOXY)TETRADECYL] BETA DEXTRO GLUCOPYRANOSYL] 3 DEOXY 3 [3 (HYDROXY)TETRADECANAMIDO] 4 O [3 (HYDROXY)TETRADECYL] DEXTRO GLYCERO DEXTRO IDO HEPTONIC ACID;
CARBOXYLIC ACID DERIVATIVE;
IMMUNOSUPPRESSIVE AGENT;
LIPID A DERIVATIVE;
UNCLASSIFIED DRUG;
ARTICLE;
CELL STRAIN U937;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
IMMUNOMODULATION;
PRIORITY JOURNAL;
REACTION ANALYSIS;
STOICHIOMETRY;
CARBOXYLIC ACIDS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
ETHERS;
HUMANS;
IMMUNOSUPPRESSIVE AGENTS;
INHIBITORY CONCENTRATION 50;
LIPID A;
LIPOPOLYSACCHARIDES;
PYRANS;
STRUCTURE-ACTIVITY RELATIONSHIP;
TUMOR NECROSIS FACTOR-ALPHA;
U937 CELLS;
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EID: 0035850130
PISSN: 00086215
EISSN: None
Source Type: Journal
DOI: 10.1016/S0008-6215(01)00134-3 Document Type: Article |
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Times cited : (14)
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References (22)
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