Angular methoxy-substituted furo- and pyranoquinolinones as blockers of the voltage-gated potassium channel Kv1.3

Journal of Medicinal Chemistry

Volumn 44, Issue 8, 2001, Pages 1249-1256

  Butenschon I ^a   Moller K ^a   Hansel W ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

8 METHOXY 2 (1' METHYLETHYL) 5 METHYL 4,5 DIHYDROFURO[3,2 C]QUINOLIN 4 ONE; 9 METHOXY 2,2,6 TRIMETHYL 2,6 DIHYDRO 5H PYRANO[3,2 C]QUINOLIN 5 ONE; FUROQUINOLINE DERIVATIVE; FUROQUINOLINONE DERIVATIVE; IMMUNOSUPPRESSIVE AGENT; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; PYRANOQUINOLINE DERIVATIVE; PYRANOQUINOLINONE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; FIBROBLAST; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; POTASSIUM CURRENT;

ANIMALS; CELL LINE; FURANS; IMMUNOSUPPRESSIVE AGENTS; KV1.3 POTASSIUM CHANNEL; MICE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; QUINOLINES; QUINOLONES; SODIUM CHANNEL BLOCKERS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035848581     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm001007u     Document Type: Article

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