Nipecotic and iso-nipecotic amides as potent and selective somatostatin subtype-2 receptor agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 3, 2001, Pages 415-417

  Zhou, Changyou ^a   Guo, Liangqin ^a   Morriello, Greg ^a   Pasternak, Alex ^a   Pan, Yanping ^a   Rohrer, Susan P ^a   Birzin, Elizebeth T ^a   Huskey, Su Er Wu ^a   Jacks, Tom ^a   Schleim, Klaus D ^a   Cheng, Kang ^a   Schaeffer, James M ^a   Patchett, Arthur A ^a   Yang, Lihu ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; BETA METHYLTRYPTOPHYLLYSINE TERT BUTYL ESTER; HORMONE RECEPTOR STIMULATING AGENT; ISONIPECOTIC ACID; ISONIPECOTIC AMIDE; NIPECOTIC ACID DERIVATIVE; RECEPTOR SUBTYPE; SOMATOSTATIN RECEPTOR; UNCLASSIFIED DRUG; UREA;

ARTICLE; BINDING AFFINITY; DRUG EFFECT; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ANIMALS; COMBINATORIAL CHEMISTRY TECHNIQUES; HUMANS; ISOMERISM; NIPECOTIC ACIDS; OLIGOPEPTIDES; PROTEIN BINDING; RECEPTORS, SOMATOSTATIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035847681     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00687-9     Document Type: Article

References (11)