Induction of phosphorylated-Stat3 following focal cerebral ischemia in mice

Neuroscience Letters

Volumn 303, Issue 3, 2001, Pages 153-156

  Wen, Tong Chun ^a   Peng, Hui ^a   Hata, Ryuji ^a   Desaki, Junzo ^a   Sakanaka, Masahiro ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Brain; DNA fragmentation; Mice; Middle cerebral artery occlusion; Stat3; Transcription factor

Indexed keywords

PROTEIN ANTIBODY; STAT3 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ISCHEMIA; BRAIN NERVE CELL; BRAIN REGION; CONTROLLED STUDY; DISEASE COURSE; IMMUNOBLOTTING; IMMUNOELECTRON MICROSCOPY; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; BRAIN ISCHEMIA; CELL DEATH; CELL MEMBRANE; CYTOKINES; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON; NERVE DEGENERATION; NEUROGLIA; NEURONS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS;

EID: 0035843971     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)01711-6     Document Type: Article

References (11)

1. STAT3 and NFkappaB activation precedes glial reactivity in the excitotoxically injured young cortex but not in the corresponding distal thalamic nuclei
2. Roles of STAT3 defined by tissue-specific gene targeting
3. Stat3 as an oncogene
4. Evolution of brain infarction after transient focal cerebral ischemia in mice
5. Activation of the JAK/STAT pathway following transient focal cerebral ischemia: Signaling through Jak1 and Stat3 in astrocytes
6. Cell swelling activates STAT1 and STAT3 proteins in cultured rat hepatocytes
7. Occurrence of a transcription factor, signal transducer and activators of transcription 3 (Stat3), in the postsynaptic density of the rat brain
8. Early increases in TNFalpha, IL-6 and IL-1 beta levels following transient cerebral ischemia in gerbil brain
9. Peripheral but not central axotomy induces changes in Janus kinases (JAK) and signal transducers and activators of transcription (STAT)
10. Pharmaceutical intervention in the JAK/STAT signaling pathway
11. Ginseng root prevents learning disability and neuronal loss in gerbils with 5 min forebrain ischemia