Overexpression of folate binding protein α is one of the mechanism explaining the adaptation of ht29 cells to high concentration of methotrexate

Cancer Letters

Volumn 171, Issue 2, 2001, Pages 139-145

  De Nonancourt Didion, Marie ^a   Guéant, Jean Louis ^a   Adjalla, Charles ^a   Chéry, Céline ^a   Hatier, Renée ^a   Namour, Farès ^a  

^a INSERM   (France)

Author keywords

Dihydrofolate reductase; Folate binding protein; Ht29 cells; Human colon adenocarcinoma; Methotrexate

Indexed keywords

COMPLEMENTARY DNA; DIHYDROFOLATE REDUCTASE; FOLATE BINDING PROTEIN; FOLIC ACID; METHOTREXATE; PROTEIN SUBUNIT;

ADAPTATION; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CANCER GROWTH; CANCER RESISTANCE; COLON ADENOCARCINOMA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA TRANSCRIPTION; HUMAN; HUMAN CELL; INTESTINE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIMETABOLITES, ANTINEOPLASTIC; CARRIER PROTEINS; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, NEOPLASM; FOLIC ACID; HT29 CELLS; HUMANS; METHOTREXATE; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL-LYASE; PHOSPHOLIPASE C; PROTEIN BINDING; PROTEIN ISOFORMS; RECEPTORS, CELL SURFACE; TETRAHYDROFOLATE DEHYDROGENASE; TRANSCRIPTION, GENETIC;

EID: 0035841013     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(01)00552-3     Document Type: Article

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