3,4-Dihydroxyphenylacetaldehyde and hydrogen peroxide generate a hydroxyl radical: Possible role in Parkinson's disease pathogenesis

Molecular Brain Research

Volumn 93, Issue 1, 2001, Pages 1-7

  Li, Shu Wen ^a   Lin, Tien Sung ^b   Minteer, Shelly ^a   Burke, William J ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

3,4 Dihydroxyphenylacetaldehyde; Free radical; Neuronal death; Parkinson's disease

Indexed keywords

3,4 DIHYDROXYPHENYLACETALDEHYDE; 3,4 DIHYDROXYPHENYLGLYCOLALDEHYDE; ALDEHYDE DERIVATIVE; AMINE OXIDASE (FLAVIN CONTAINING); CATECHOLAMINE; DOPAMINE; FREE RADICAL; HEAVY METAL; HYDROGEN PEROXIDE; HYDROXYL RADICAL; IRON; NORADRENALIN; UNCLASSIFIED DRUG;

AGED; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CASE REPORT; CELL DEATH; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; DEGENERATIVE DISEASE; ELECTROCHEMICAL DETECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; HYDROXYLATION; MALE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NEUROTOXICITY; OXIDATION REDUCTION POTENTIAL; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; SCREENING; SUBSTANTIA NIGRA;

3,4-DIHYDROXYPHENYLACETIC ACID; AGED; ALDEHYDES; BRAIN; HUMANS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MALE; NERVE DEGENERATION; PARKINSON DISEASE; SPECTROPHOTOMETRY, ATOMIC;

GYMNOMYZA SAMOENSIS;

EID: 0035840318     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(01)00120-6     Document Type: Article

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