7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures

Phytochemistry

Volumn 58, Issue 1, 2001, Pages 53-58

  Katano, Nobuyuki ^a   Yamamoto, Hirobumi ^b   Iio, Reiko ^a   Inoue, Kenichiro ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

7 Deoxyloganin; 7 Deoxyloganin 7 hydroxylase; Biosynthesis; Caprifoliaceae; Cell suspension cultures; Cytochrome P450; Enzyme; Iridoid glucoside; Loganin; Lonicera japonica

Indexed keywords

7 DEOXYLOGANIN; 7 DEOXYLOGANIN 7 HYDROXYLASE; 7-DEOXYLOGANIN 7-HYDROXYLASE; CARBON MONOXIDE; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; ENZYME INHIBITOR; GLUCOSIDE; KETOCONAZOLE; LOGANIN; METYRAPONE; MICONAZOLE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXYGEN; OXYGENASE; PYRAN DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ANGIOSPERM; ARTICLE; CATALYSIS; CELL CULTURE; CELL SUSPENSION; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SYNTHESIS; ENZYMOLOGY; LONICERA JAPONICA; METABOLISM; MICROSOME; NONHUMAN; OXYGEN CONSUMPTION; PLANT;

ANGIOSPERMS; CARBON MONOXIDE; CELLS, CULTURED; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INHIBITORS; GLUCOSIDES; IRIDOIDS; KETOCONAZOLE; METYRAPONE; MICONAZOLE; MICROSOMES; MIXED FUNCTION OXYGENASES; NADP; OXYGEN; OXYGEN CONSUMPTION; PYRANS;

CAPRIFOLIACEAE; JAPONICA; LONICERA JAPONICA;

EID: 0035839086     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(01)00181-9     Document Type: Article

References (31)

1. Biosynthesis of the indole and colchicum alkaloids
2. Preparation and isolation of deoxyloganin: Its role as precursor of loganin and the indole alkaloids
3. Untersuchungen zur biogenese der indolalkaloide. Synthese und verfüetterung radioaktiv markierter hydroxyloganin-derivate
4. Iridoids XXV. New iridoid glucosides from Rubiaceae
5. Secogalioside, an iridoid glucoside from Galium album Mill. and carbon-13 NMR spectra of some secoiridoid glucosides
6. Plant cytochrome P450
7. Cytochrome P-450 dependent (+)-limonene-6-hydroxylation in fruits of caraway (Carum carvi)
8. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
9. 2-Oxoglutarate-dependent dioxygenase and related enzymes: Biochemical characterization
10. Properties of a mixed function oxygenase catalyzing ipomeamarone 15-hydroxylation in microsomes from cut-injured and Ceratocystis fimbriata-infected sweet potato root tissues
11. Introduction and characterization of a cytochrome P-450-dependent camphor hydroxylase in tissue cultures of common sage (Salvia officinalis)
12. Cytochrome P-450 catalyzed monoterpene hydroxylation in Nepeta mussinii
13. Hyoscyamine 6β-hydroxylase, a 2-oxoglutarate-dependent dioxygenase, in alkaloid-producing root cultures
14. On the possibility of the intermediacy of 10-hydroxyloganin in the biosynthesis of secologanin
15. Intermediacy of 6-hydroxyloganin in the ring cleavage course of loganin to secologanin
16. Metabolism of monoterpenes: Demonstration of the hydroxylation of (+)-sabinene to (+)-cis-sabinol by an enzyme preparation from sage (Salvia officinals) leaves
17. Monoterpene biosynthesis: Specificity of the hydroxylations of (-)-limonene by enzyme preparations from peppermint (Mentha piperita), spearmint (Mentha spicata), and perila (Perilla frutescens) leaves
18. Iridoid glucosides from Lonicera japonica THUNB
19. Induction and characterization of a NADPH-dependent flavone synthase from cell cultures of soybean
20. Differential effects of the imidazole derivatives etomidate, ketoconazole and miconazole and of metyrapone on the secretion of cortisol and its precursors by human adrenocortical cells
21. S-Adenosyl-L-methionine: Loganic acid methyltransferase
22. Revised medium for rapid growth and bioassays with tobacco tissue cultures
23. The carbon monoxide-binding pigment of liver microsomes I. Evidence for its hemoprotein nature
24. Strctural studies of metyrapone: A potent inhibitor of cytochrome P-450
25. Biosynthesis of iridoid glucosides in Galium mollugo, G. spurium var. echinospermon and Deutzia crenata. Intermediacy of deoxyloganic acid, loganin and iridodial glucoside
26. Iridoid glucosides from Gallium mollugo
27. Transformation of loganin and 7-deoxyloganin into secologanin by Lonicera japonica cell suspension cultures
28. Secologanin synthase which catalyzes the oxidative cleavage of loganin into secologanin is a cytochrome P450
29. Differential response of cultured parsley cells to elicitors from two non-pathogenic strains of fungi
30. Isovimcoside (Strictosidine), the key intermediate in the enzymatic formation of indole alkaloids
31. Enzymatic synthesis of ajmalicine and related indole alkaloids