Genomic structure and loss of heterozygosity of EPHB2 in colorectal cancer

Cancer Letters

Volumn 164, Issue 1, 2001, Pages 97-104

  Oba, Sueli M ^a,b   Wang, You Jie ^a   Song, Jain Ping ^a   Li, Zhong You ^a   Kobayashia, Keiko ^a   Tsuganec, Shoichiro ^c   Hamadab, Gerson S ^b   Tanaka, Masamitsu ^a   Sugimura, Haruhiko ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Hospital Santa Cruz   (Brazil)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Colorectal tumor; EphB2; Genomic structure; Loss of heterozygosity; Polymorphism

Indexed keywords

PROTEIN P53; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE EPHB2; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHINESE; CHROMOSOME 1P; COLORECTAL CANCER; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE DELETION; GENE LOCATION; GENE MUTATION; GENE OVEREXPRESSION; GENOME; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; JAPAN; MALE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

AGED; ALLELES; AUSTRALIA; CHINA; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 1; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; EXONS; FEMALE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; INTRONS; JAPAN; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPHB2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEX FACTORS; SWITZERLAND; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 0035836082     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(00)00716-3     Document Type: Article

References (16)

1. Unified nomenclature for Eph family receptors and their ligands, the ephrins
2. Identification of protein-tyrosine kinase genes preferentially expressed in embryo stomach and gastric cancer
3. Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors
4. Identification of the human ERK gene as a putative receptor tyrosine kinase and its chromosomal localization to 1p36.1: A comparative mapping of human, mouse, and rat chromosomes
5. Molecular characterization and chromosomal localization of DRT (EPHT3): A developmentally regulated human protein-tyrosine kinase gene of the EPH family
6. Loss of heterozygosity at chromosome 1p in different solid human tumors: Association with survival
7. Deletion mapping defines different regions in 1p34.2-pter that may harbor genetic information related to human colorectal cancer
8. Detailed deletion mapping on chromosome 1p32-1p36 in human colorectal cancer: Identification of three distinct regions of common allelic loss
9. Coexpression of transcripts encoding EPHB receptor protein tyrosine kinases and their ephrin-B ligands in human small cell lung carcinoma
10. Genomic organization and alternatively processed forms of Cek5, a receptor protein-tyrosine kinase of the Eph subfamily
11. Analysis of the VNTR locus D1S80 by the PCR followed by high-resolution PAGE
12. A comprehensive genetic map of the human genome based on 5,264 microsatellites
13. Human colorectal cancer: High frequency of deletions at chromosome 1p35
14. Chromosome 1 in human colorectal tumors. Cytogenetic research on structural changes and their significance
15. Suppression of tumourigenicity in human colon carcinoma cells by introduction of normal chromosome 1p36 region
16. Candidate tumor suppressor RIZ is frequently involved in colorectal carcinogenesis