Results of treatment with 2-chlorodeoxyadenosine in refractory or relapsed langerhans cell histiocytosis study of 9 patients;Resultados del tratamiento con 2-clorodesoxiadenosina en la histiocitosis de células de langerhans resistente o en recaída. Estudio de 9 pacientes

Medicina Clinica

Volumn 116, Issue 9, 2001, Pages 339-342

  Grau, Javier ^a   Ribera, Josep Maria ^a   Tormo, Mar ^a   Indiano, José María ^b   Verche, Javier ^d   Sandoval, Virgilio ^e   Ramírez, Gemma ^f   Sastre, Ana ^g   Flores, Eduardo ^h   García Conde, Javier ^c  

^a Hospital Universitary Germans Trias I Pujol   (Spain)

^b HOSPITAL DE BASURTO   (Spain)

^c HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^d HOSPITAL CAN MISSES   (Spain)

^e Hospital Virgen Blanca   (Spain)

^f HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

^g HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^h HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

Author keywords

2 chlorodeoxyadenosine (2 CdA); Langerhans cell histiocytosis (LCH); Refractory; Relapsed

Indexed keywords

CLADRIBINE;

ADULT; ARTICLE; BONE MARROW SUPPRESSION; CLINICAL ARTICLE; DOSE RESPONSE; FEMALE; HISTIOCYTOSIS X; HUMAN; MALE; PRESCHOOL CHILD; RELAPSE;

EID: 0035835898     PISSN: 00257753     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0025-7753(01)71821-0     Document Type: Article

References (28)

1. Langerhans cell histiocytosis (histiocytosis X) a clonal proliferative disease
2. Detection of clonal histiocytes in Langerhans cells histiocytosis: Biology and clinical significance
3. Histiocitosis de células de Langerhans: Una perspectiva clínico-patológica
4. Cyclosporine therapy for refractory Langerhans cell histiocytosis
5. Myeloablative therapy and bone marrow transplantation for Langerhans cell histiocytosis
6. Hematopoietic stem cell transplantation for Langerhans cell histiocytosis in Japan
7. Monoclonal antibody therapy in Langerhans cell histiocytosis feasible and reasonable?
8. Diagnostic guidelines for hemophagocytic lymphohistiocytosis
9. Cladribine activity in adult Langerhans cell histiocytosis
10. Nonparametric estimation from incomplete observations
11. The epidemiology of Langerhans cell histiocytosis in children in Denmark, 1975-1989
12. Langerhans cell histiocytosis in adults
13. Langerhans cell histiocytosis in the adult
14. Central nervous system disease in Langerhans cell histiocytosis
15. Intralesional infiltration of corticosteroids in localised Langerhans cell histiocytosis
16. Topical nitrogen mustard: An effective treatment for cutaneous Langerhans cell histiocytosis
17. Langerhans cell histiocytosis-I: A randomized trial of etoposide versus vinblastine in disseminated Langerhans cell histiocytosis
18. Langerhans cell histiocytosis in childhood: Results from the Italian Cooperative AIEOP-CNR-HX 83 study
19. A treatment strategy for disseminated Langerhans cell histiocytosis. DAL HX-83 Study Group
20. Current therapy for Langerhans cell histiocytosis
21. Histiocitosis de células de Langerhans. Protocolo SEOP-HCL96
22. Potent toxicity of 2-chlorodeoxyadenosine towards human monocytes in vitro and in vivo. A novel approach to immunosuppressive therapy
23. 2-Chlorodeoxyadenosine induced complete remissions in Langerhans cell histiocytosis
24. Treatment of Langerhans cell histiocytosis with 2-chlorodeoxyadenosine
25. 2-chlorodeoxyadenosine (2-CdA) for the treatment of refractory or recurrent Langerhans cell histiocytosis (LCH) in pediatric patients
26. The relation of Langerhans cell histiocytosis to acute leukemia, lymphomas, and other solid tumors
27. Risk of secondary leukemia after treatment with etoposide (VP-16) for Langerhans cell histiocytosis in Italian and Austrian-German populations
28. Inhibition of DNA repair by deoxyadenosine in resting human lymphocytes