Synthesis of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid analogues modified at the C-4 and C-9 positions and their behaviour towards sialidase from influenza virus and pig liver membrane

Carbohydrate Research

Volumn 330, Issue 1, 2001, Pages 31-41

  Ikeda, Kiyoshi ^a   Sano, Kimihiko ^a   Ito, Masaki ^a   Saito, Megumi ^a   Hidari, Kazuya ^a   Suzuki, Takashi ^a   Suzuki, Yasuo ^a   Tanaka, Kiyoshi ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Cyanomethyl group; Influenza virus sialidase; Mammalian sialidase; Sialic acid; Sialidase inhibitor

Indexed keywords

2 DEOXY 2,3 DIDEHYDRO N ACETYLNEURAMINIC ACID DERIVATIVE; 5 ACETAMIDO 2,6 ANHYDRO 4 O CARBAMOYLMETHYL 3,5 DIDEOXY DEXTRO GLYCERO DEXTRO GALACTO NON 2 ENONIC ACID; 5 ACETAMIDO 2,6 ANHYDRO 4 O CYANOMETHYL 3,5 DIDEOXY DEXTRO GLYCERO DEXTRO GALACTO NON 2 ENONIC ACID; 5 ACETAMIDO 2,6 ANHYDRO 9 AZIDO 3,5,9 TRIDEOXY 4 O METHOXYIMINOMETHYL DEXTRO GLYCERO DEXTRO GALACTO NON 2 ENONIC ACID; 5 ACETAMIDO 2,6 ANHYDRO 9 AZIDO 4 O CARBAMOYLMETHYL 3,5,9 TRIDEOXY DEXTRO GLYCERO DEXTRO GALACTO NON 2 ENONIC ACID; 5 ACETAMIDO 2,6 ANHYDRO 9 AZIDO 4 O CYANOMETHYL 3,5,9 TRIDEOXY DEXTRO GLYCERO DEXTRO GALACTO NON 2 ENONIC ACID; 5 ACETAMIDO 4 O AMIDINOMETHYL 2,6 ANHYDRO 3,5 DIDEOXY DEXTRO GLYCERO DEXTRO GALACTO NON 2 ENONIC ACID; 5 ACETAMIDO 4 O AMIDINOMETHYL 2,6 ANHYDRO 9 AZIDO 3,5,9 TRIDEOXY DEXTRO GLYCERO DEXTRO GALACTO NON 2 ENONIC ACID; 5,9 DIACETAMIDO 2,6 ANHYDRO 3,5,9 TRIDEOXY 4 O THIOCARBAMOYLMETHYL DEXTRO GLYCERO DEXTRO GALACTO NON 2 ENONIC ACID; 5,9 DIACETAMIDO 2,6 ANHYDRO 4 O AMIDINOMETHYL 3,5 DIDEOXY DEXTRO GLYCERO DEXTRO GALACTO NON 2 ENONIC ACID; 5,9 DIACETAMIDO 2,6 ANHYDRO 4 O CARBAMOYLMETHYL 3,5 DIDEOXY DEXTRO GLYCERO DEXTRO GALACTO NON 2 ENONIC ACID; 5,9 DIACETAMIDO 4 O CYANOMETHYL 2,6 ANHYDRO 3,5 DIDEOXY DEXTRO GLYCERO DEXTRO GALACTO NON 2 ENONIC ACID; HYDROXYL GROUP; N ACETYLNEURAMINIC ACID DERIVATIVE; SIALIDASE; SIALIDASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARBOHYDRATE SYNTHESIS; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MODIFICATION; ENZYME STRUCTURE; INFLUENZA VIRUS A; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; SWINE;

ANIMALS; CELL MEMBRANE; ENZYME INHIBITORS; LIVER; N-ACETYLNEURAMINIC ACID; NEURAMINIDASE; ORTHOMYXOVIRIDAE; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

INFLUENZA VIRUS; INFLUENZAVIRUS A; MAMMALIA; SUS SCROFA;

EID: 0035835014     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6215(00)00267-6     Document Type: Article

References (20)