Structure Prediction and Active Site Analysis of the Metal Binding Determinants in γ-Glutamylcysteine Synthetase

Journal of Biological Chemistry

Volumn 276, Issue 45, 2001, Pages 42099-42107

  Abbott, Jared J ^a   Pei, Jimin ^a   Ford, Jennifer L ^a   Qi, Yuan ^a   Grishin, Vyacheslav N ^a   Pitcher, Lisa A ^a   Phillips, Margaret A ^a   Grishin, Nick V ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; CATALYSIS; CELLS; HYDROLYSIS; METALS;

LIGANDS;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATE; CARBOXYLIC ACID; GLUTAMATE AMMONIA LIGASE; GLUTAMATE CYSTEINE LIGASE; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; LIGAND; LIGASE; MAGNESIUM; MANGANESE; METAL; MUTANT PROTEIN; PEPTIDE; PHOSPHORUS; PROTEIN E489A; PROTEIN Q321A; SPERMIDINE; TRYPANOTHIONE; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME MECHANISM; GLUTATHIONE METABOLISM; METAL BINDING; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TRYPANOSOMA BRUCEI; AMINO ACID SEQUENCE; BINDING SITE; CHEMISTRY; KINETICS; MOLECULAR GENETICS;

TRYPANOSOMA; TRYPANOSOMA BRUCEI;

AMINO ACID SEQUENCE; BINDING SITES; GLUTAMATE-AMMONIA LIGASE; GLUTAMATE-CYSTEINE LIGASE; KINETICS; MAGNESIUM; MANGANESE; MOLECULAR SEQUENCE DATA;

EID: 0035834745     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104672200     Document Type: Article

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